Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma.

Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle glaucoma.

Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide, with elevated intraocular pressure as an important risk factor. Increased resistance to outflow of aqueous humor through the trabecular meshwork causes elevated intraocular pressure, but the specific mechanisms are unknown...

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Bibliographic Details
Main Authors: John Kuchtey, Lana M Olson, Tommy Rinkoski, Edward O Mackay, T M Iverson, Kirk N Gelatt, Jonathan L Haines, Rachel W Kuchtey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1001306&type=printable
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