Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression

Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression

Xist, a pivotal player in X chromosome inactivation (XCI), has long been perceived as a cis-acting long noncoding RNA that binds exclusively to the inactive X chromosome (Xi). However, Xist’s ability to diffuse under select circumstances has also been documented, leading us to suspect that Xist RNA...

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Bibliographic Details
Main Authors: Shengze Yao, Yesu Jeon, Barry Kesner, Jeannie T Lee
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-06-01
Series:eLife
Subjects:
Xist RNA
Repeat B
X1 inhibitor
autosomal targets
Online Access:https://elifesciences.org/articles/101197
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