Effects of a Novel Formulation on Oral Biofilm, pH Buffering, and Gingival Health in Patients with Dry Mouth
Goal. To identify in patients with dry mouth the effects of a novel test agent (Oral Essentials Hydrating Formula Mouthwash, Beverly Hills, CA) versus a control agent (Biotène Dry Mouth Oral Rinse, GlaxoSmithKline Consumer Healthcare L.P., Moon Township, PA, USA) versus no treatment on dry mouth, pl...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | International Journal of Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2018/2748274 |
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| _version_ | 1850232213825650688 |
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| author | Thair Takesh Jessica Ho Miracle Vania Firmalino Delaney Islip Afarin Anbarani Petra Wilder-Smith |
| author_facet | Thair Takesh Jessica Ho Miracle Vania Firmalino Delaney Islip Afarin Anbarani Petra Wilder-Smith |
| author_sort | Thair Takesh |
| collection | DOAJ |
| description | Goal. To identify in patients with dry mouth the effects of a novel test agent (Oral Essentials Hydrating Formula Mouthwash, Beverly Hills, CA) versus a control agent (Biotène Dry Mouth Oral Rinse, GlaxoSmithKline Consumer Healthcare L.P., Moon Township, PA, USA) versus no treatment on dry mouth, plaque, salivary pH and buffering capacity, gingival health, and tooth sensitivity. Materials and Methods. In this cross-over study, ten subjects with dry mouth used test and control dry mouth interventions, as well as no dry mouth intervention in randomized sequence. Plaque Index, Gingival Index, Sulcus Bleeding Index, Plaque staining, and photographs were recorded at baseline and end of each study arm. Salivary volume, pH, and buffering capacity were also recorded at these time points. Additionally, subjects completed a questionnaire for dry mouth and dentinal sensitivity at each visit. Results. Reductions in plaque presence and clinical indices were similar after use of test or control products (p<0.05). Saliva volume and pH buffering improved significantly after use of test and control products (p<0.05). Conclusions. The effects of a novel dry mouth intervention are similar to those of an existing OTC remedy and are significantly better than no intervention. |
| format | Article |
| id | doaj-art-0a0fd15f21494c8fbddde6af3225bdb0 |
| institution | OA Journals |
| issn | 1687-8728 1687-8736 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Dentistry |
| spelling | doaj-art-0a0fd15f21494c8fbddde6af3225bdb02025-08-20T02:03:16ZengWileyInternational Journal of Dentistry1687-87281687-87362018-01-01201810.1155/2018/27482742748274Effects of a Novel Formulation on Oral Biofilm, pH Buffering, and Gingival Health in Patients with Dry MouthThair Takesh0Jessica Ho1Miracle Vania Firmalino2Delaney Islip3Afarin Anbarani4Petra Wilder-Smith5Beckman Laser Institute, University of California, Irvine, CA 92612, USABeckman Laser Institute, University of California, Irvine, CA 92612, USABeckman Laser Institute, University of California, Irvine, CA 92612, USABeckman Laser Institute, University of California, Irvine, CA 92612, USABeckman Laser Institute, University of California, Irvine, CA 92612, USABeckman Laser Institute, University of California, Irvine, CA 92612, USAGoal. To identify in patients with dry mouth the effects of a novel test agent (Oral Essentials Hydrating Formula Mouthwash, Beverly Hills, CA) versus a control agent (Biotène Dry Mouth Oral Rinse, GlaxoSmithKline Consumer Healthcare L.P., Moon Township, PA, USA) versus no treatment on dry mouth, plaque, salivary pH and buffering capacity, gingival health, and tooth sensitivity. Materials and Methods. In this cross-over study, ten subjects with dry mouth used test and control dry mouth interventions, as well as no dry mouth intervention in randomized sequence. Plaque Index, Gingival Index, Sulcus Bleeding Index, Plaque staining, and photographs were recorded at baseline and end of each study arm. Salivary volume, pH, and buffering capacity were also recorded at these time points. Additionally, subjects completed a questionnaire for dry mouth and dentinal sensitivity at each visit. Results. Reductions in plaque presence and clinical indices were similar after use of test or control products (p<0.05). Saliva volume and pH buffering improved significantly after use of test and control products (p<0.05). Conclusions. The effects of a novel dry mouth intervention are similar to those of an existing OTC remedy and are significantly better than no intervention.http://dx.doi.org/10.1155/2018/2748274 |
| spellingShingle | Thair Takesh Jessica Ho Miracle Vania Firmalino Delaney Islip Afarin Anbarani Petra Wilder-Smith Effects of a Novel Formulation on Oral Biofilm, pH Buffering, and Gingival Health in Patients with Dry Mouth International Journal of Dentistry |
| title | Effects of a Novel Formulation on Oral Biofilm, pH Buffering, and Gingival Health in Patients with Dry Mouth |
| title_full | Effects of a Novel Formulation on Oral Biofilm, pH Buffering, and Gingival Health in Patients with Dry Mouth |
| title_fullStr | Effects of a Novel Formulation on Oral Biofilm, pH Buffering, and Gingival Health in Patients with Dry Mouth |
| title_full_unstemmed | Effects of a Novel Formulation on Oral Biofilm, pH Buffering, and Gingival Health in Patients with Dry Mouth |
| title_short | Effects of a Novel Formulation on Oral Biofilm, pH Buffering, and Gingival Health in Patients with Dry Mouth |
| title_sort | effects of a novel formulation on oral biofilm ph buffering and gingival health in patients with dry mouth |
| url | http://dx.doi.org/10.1155/2018/2748274 |
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