Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature
Herpes simplex virus (HSV) is a rare cause of hepatitis in pregnancy and the chronically immunosuppressed, with a high propensity to progress to acute liver failure (ALF) and death. Patients typically present with a nonspecific clinical picture that often delays diagnosis and treatment, contributing...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/8613840 |
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| _version_ | 1832547683670163456 |
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| author | Amna Ahmed Alejandro Granillo Ethan Burns Kerri Glassner Nishath Naseem Christopher Force Suzanne M. Crumley Ashley Drews |
| author_facet | Amna Ahmed Alejandro Granillo Ethan Burns Kerri Glassner Nishath Naseem Christopher Force Suzanne M. Crumley Ashley Drews |
| author_sort | Amna Ahmed |
| collection | DOAJ |
| description | Herpes simplex virus (HSV) is a rare cause of hepatitis in pregnancy and the chronically immunosuppressed, with a high propensity to progress to acute liver failure (ALF) and death. Patients typically present with a nonspecific clinical picture that often delays diagnosis and treatment, contributing to the high mortality rate. We present a case of a young female on chronic prednisone and hydroxychloroquine for systemic lupus erythematosus (SLE) who was diagnosed with HSV-2 hepatitis after presenting with right-sided chest and abdominal discomfort. Despite early clinical deterioration, prompt initiation of therapy with intravenous acyclovir and methylprednisolone led to rapid improvement. |
| format | Article |
| id | doaj-art-09ff8a1b490f475999022a5a43954698 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-09ff8a1b490f475999022a5a439546982025-02-03T06:43:40ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/86138408613840Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the LiteratureAmna Ahmed0Alejandro Granillo1Ethan Burns2Kerri Glassner3Nishath Naseem4Christopher Force5Suzanne M. Crumley6Ashley Drews7Houston Methodist Hospital, Department of Medicine, 6550 Fannin Street, Houston, TX 77030, USAHouston Methodist Hospital, Department of Medicine, 6550 Fannin Street, Houston, TX 77030, USAHouston Methodist Hospital, Department of Medicine, 6550 Fannin Street, Houston, TX 77030, USAHouston Methodist Hospital, Department of Gastroenterology and Hepatology, Houston, TX 77030, USAHouston Methodist Hospital, Department of Medicine, 6550 Fannin Street, Houston, TX 77030, USAHouston Methodist Hospital, Department of Medicine, 6550 Fannin Street, Houston, TX 77030, USAHouston Methodist Hospital, Department of Pathology and Genomic Medicine, Houston, TX 77030, USAHouston Methodist Hospital, Department of Infectious Diseases, Houston, TX 77030, USAHerpes simplex virus (HSV) is a rare cause of hepatitis in pregnancy and the chronically immunosuppressed, with a high propensity to progress to acute liver failure (ALF) and death. Patients typically present with a nonspecific clinical picture that often delays diagnosis and treatment, contributing to the high mortality rate. We present a case of a young female on chronic prednisone and hydroxychloroquine for systemic lupus erythematosus (SLE) who was diagnosed with HSV-2 hepatitis after presenting with right-sided chest and abdominal discomfort. Despite early clinical deterioration, prompt initiation of therapy with intravenous acyclovir and methylprednisolone led to rapid improvement.http://dx.doi.org/10.1155/2020/8613840 |
| spellingShingle | Amna Ahmed Alejandro Granillo Ethan Burns Kerri Glassner Nishath Naseem Christopher Force Suzanne M. Crumley Ashley Drews Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature Case Reports in Medicine |
| title | Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature |
| title_full | Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature |
| title_fullStr | Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature |
| title_full_unstemmed | Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature |
| title_short | Herpes Simplex Virus-2 Hepatitis: A Case Report and Review of the Literature |
| title_sort | herpes simplex virus 2 hepatitis a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2020/8613840 |
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