Child and Adult Seborrheic Dermatitis: A Narrative Review of the Current Treatment Landscape
Abstract Introduction Seborrheic dermatitis (SD) is a common, chronic inflammatory skin condition affecting sebaceous gland-rich areas of the skin. The multifactorial etiology of SD involves sebocyte activity, skin microbiome dysbiosis, and immune factors. Various treatment options exist for managem...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Adis, Springer Healthcare
2025-02-01
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| Series: | Dermatology and Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s13555-025-01351-z |
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| Summary: | Abstract Introduction Seborrheic dermatitis (SD) is a common, chronic inflammatory skin condition affecting sebaceous gland-rich areas of the skin. The multifactorial etiology of SD involves sebocyte activity, skin microbiome dysbiosis, and immune factors. Various treatment options exist for management of SD. Methods A PubMed search conducted on November 1, 2024 using the terms “seborrheic dermatitis” and “treatment” (restricted to 2019–2024) yielded 389 results, from which relevant papers and additional references were included in this review. Discussion Topical antifungals, topical corticosteroids, and topical calcineurin inhibitors are first-line treatments for SD; however, long-term use of each of these may be limited by varying side effects. Roflumilast foam is a newly approved topical with potential to become a first-line treatment. Myriad systemic treatments exist as second- and third-line treatments for cases of moderate-to-severe and/or recalcitrant SD. Procedural interventions of varying efficacy exist. Conclusions The treatment of SD requires an individualized approach, utilizing a range of topical, systemic, and procedural interventions. The advent of new treatments like roflumilast foam offers novel, well-tolerated, and safer options than what has been available in the past. |
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| ISSN: | 2193-8210 2190-9172 |