Prognostic Value and Correlation Between WT1 Overexpression and NPM1 Mutation in Patients with Acute Myeloblastic Leukemia

Prognostic Value and Correlation Between WT1 Overexpression and NPM1 Mutation in Patients with Acute Myeloblastic Leukemia

Background. Acute myeloblastic leukemia (AML) with NPM1 mutation amounts to 30 % of all AML and is characterized by good prognosis with the exception of cases with FLT3-ITD mutation. Despite the good prognosis, the likelihood of relapses in patients with NPM1 mutation may significantly differ. Thus,...

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Bibliographic Details
Main Authors: LL Girshova, IG Budaeva, EG Ovsyannikova, SO Kuzin, DV Motorin, RSh Badaev, DB Zammoeva, VV Ivanov, KV Bogdanov, OS Pisotskaya, YuV Mirolyubova, TS Nikulina, YuA Alekseeva, AYu Zaritskii
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2017-10-01
Series:Клиническая онкогематология
Subjects:
acute myeloblastic leukemia
AML
NPM1
WT1
molecular monitoring
Online Access:http://bloodjournal.ru/wp-content/uploads/2017/10/8_1.pdf
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