Sulfasalazine-Induced Epstein–Barr Virus-Positive Mucocutaneous Ulcer
Epstein–Barr virus (EBV) may cause a wide spectrum of symptomatology in humans ranging from asymptomatic upper respiratory tract infection to infectious mononucleosis and in more severe cases lymphoproliferative disorders or hemophagocytic lymphohistiocytosis. Its neoplastic potential is higher in i...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2024/6883657 |
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| author | Cedric Stabel F. J. Sherida H. Woei-A-Jin Thomas Tousseyn Maria Garmyn |
| author_facet | Cedric Stabel F. J. Sherida H. Woei-A-Jin Thomas Tousseyn Maria Garmyn |
| author_sort | Cedric Stabel |
| collection | DOAJ |
| description | Epstein–Barr virus (EBV) may cause a wide spectrum of symptomatology in humans ranging from asymptomatic upper respiratory tract infection to infectious mononucleosis and in more severe cases lymphoproliferative disorders or hemophagocytic lymphohistiocytosis. Its neoplastic potential is higher in immunocompromised individuals. We describe a case of EBV-positive mucocutaneous ulcer, a more indolent clinical entity on the spectrum of EBV-driven lymphoproliferative disorders, and are one of the first to put sulfasalazine, an immunomodulatory agent, forward as the possible culprit. |
| format | Article |
| id | doaj-art-09f26ef29a3d48e487f7a63b1875bc1d |
| institution | OA Journals |
| issn | 2090-6579 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-09f26ef29a3d48e487f7a63b1875bc1d2025-08-20T02:03:16ZengWileyCase Reports in Hematology2090-65792024-01-01202410.1155/2024/6883657Sulfasalazine-Induced Epstein–Barr Virus-Positive Mucocutaneous UlcerCedric Stabel0F. J. Sherida H. Woei-A-Jin1Thomas Tousseyn2Maria Garmyn3Department of DermatologyDepartment of General Medical OncologyDepartment of PathologyDepartment of DermatologyEpstein–Barr virus (EBV) may cause a wide spectrum of symptomatology in humans ranging from asymptomatic upper respiratory tract infection to infectious mononucleosis and in more severe cases lymphoproliferative disorders or hemophagocytic lymphohistiocytosis. Its neoplastic potential is higher in immunocompromised individuals. We describe a case of EBV-positive mucocutaneous ulcer, a more indolent clinical entity on the spectrum of EBV-driven lymphoproliferative disorders, and are one of the first to put sulfasalazine, an immunomodulatory agent, forward as the possible culprit.http://dx.doi.org/10.1155/2024/6883657 |
| spellingShingle | Cedric Stabel F. J. Sherida H. Woei-A-Jin Thomas Tousseyn Maria Garmyn Sulfasalazine-Induced Epstein–Barr Virus-Positive Mucocutaneous Ulcer Case Reports in Hematology |
| title | Sulfasalazine-Induced Epstein–Barr Virus-Positive Mucocutaneous Ulcer |
| title_full | Sulfasalazine-Induced Epstein–Barr Virus-Positive Mucocutaneous Ulcer |
| title_fullStr | Sulfasalazine-Induced Epstein–Barr Virus-Positive Mucocutaneous Ulcer |
| title_full_unstemmed | Sulfasalazine-Induced Epstein–Barr Virus-Positive Mucocutaneous Ulcer |
| title_short | Sulfasalazine-Induced Epstein–Barr Virus-Positive Mucocutaneous Ulcer |
| title_sort | sulfasalazine induced epstein barr virus positive mucocutaneous ulcer |
| url | http://dx.doi.org/10.1155/2024/6883657 |
| work_keys_str_mv | AT cedricstabel sulfasalazineinducedepsteinbarrviruspositivemucocutaneousulcer AT fjsheridahwoeiajin sulfasalazineinducedepsteinbarrviruspositivemucocutaneousulcer AT thomastousseyn sulfasalazineinducedepsteinbarrviruspositivemucocutaneousulcer AT mariagarmyn sulfasalazineinducedepsteinbarrviruspositivemucocutaneousulcer |