Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria

Jaundice commonly occurs in severe malaria, seen in approximately 2,5% patients with falciparum malaria infection. Jaundice in malaria can be caused by intravascular hemolysis, disseminated intravascular coagulation (DIC) or malaria-related liver disorders. Malaria hepatopathy is a term that is ofte...

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Main Authors: Muhammad Vitanata Arfijanto, Mohammad Imam Wahyudi
Format: Article
Language:English
Published: Interna Publishing 2023-11-01
Series:The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Subjects:
Online Access:https://ina-jghe.com/index.php/jghe/article/view/789
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author Muhammad Vitanata Arfijanto
Mohammad Imam Wahyudi
author_facet Muhammad Vitanata Arfijanto
Mohammad Imam Wahyudi
author_sort Muhammad Vitanata Arfijanto
collection DOAJ
description Jaundice commonly occurs in severe malaria, seen in approximately 2,5% patients with falciparum malaria infection. Jaundice in malaria can be caused by intravascular hemolysis, disseminated intravascular coagulation (DIC) or malaria-related liver disorders. Malaria hepatopathy is a term that is often used to describe hepatocytic dysfunction in severe malaria, although inflammation does not occur in the liver parenchyma.  Malaria hepatopathy also characterized by a rise in serum bilirubin along with the rise in serum glutamate pyruvate trasnaminase levels. This two condition are similar but must be distinguished because of different treatment required.
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series The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
spelling doaj-art-09ed005fedd5412c80f8d8ddc37415fd2025-08-20T02:25:59ZengInterna PublishingThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy1411-48012302-81812023-11-0124217217510.24871/2422023172-175829Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum MalariaMuhammad Vitanata Arfijanto0Mohammad Imam Wahyudi1Division of Tropical Infectious Disease, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, SurabayaDepartment of Internal Medicine, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, SurabayaJaundice commonly occurs in severe malaria, seen in approximately 2,5% patients with falciparum malaria infection. Jaundice in malaria can be caused by intravascular hemolysis, disseminated intravascular coagulation (DIC) or malaria-related liver disorders. Malaria hepatopathy is a term that is often used to describe hepatocytic dysfunction in severe malaria, although inflammation does not occur in the liver parenchyma.  Malaria hepatopathy also characterized by a rise in serum bilirubin along with the rise in serum glutamate pyruvate trasnaminase levels. This two condition are similar but must be distinguished because of different treatment required.https://ina-jghe.com/index.php/jghe/article/view/789malaria hepatopathyjaundicesevere malariafalciparum malaria
spellingShingle Muhammad Vitanata Arfijanto
Mohammad Imam Wahyudi
Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
malaria hepatopathy
jaundice
severe malaria
falciparum malaria
title Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria
title_full Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria
title_fullStr Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria
title_full_unstemmed Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria
title_short Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria
title_sort malaria hepatopathy and thrombocytopenia in severe falciparum malaria
topic malaria hepatopathy
jaundice
severe malaria
falciparum malaria
url https://ina-jghe.com/index.php/jghe/article/view/789
work_keys_str_mv AT muhammadvitanataarfijanto malariahepatopathyandthrombocytopeniainseverefalciparummalaria
AT mohammadimamwahyudi malariahepatopathyandthrombocytopeniainseverefalciparummalaria