Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria

Jaundice commonly occurs in severe malaria, seen in approximately 2,5% patients with falciparum malaria infection. Jaundice in malaria can be caused by intravascular hemolysis, disseminated intravascular coagulation (DIC) or malaria-related liver disorders. Malaria hepatopathy is a term that is ofte...

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Bibliographic Details
Main Authors: Muhammad Vitanata Arfijanto, Mohammad Imam Wahyudi
Format: Article
Language:English
Published: Interna Publishing 2023-11-01
Series:The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
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Online Access:https://ina-jghe.com/index.php/jghe/article/view/789
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Summary:Jaundice commonly occurs in severe malaria, seen in approximately 2,5% patients with falciparum malaria infection. Jaundice in malaria can be caused by intravascular hemolysis, disseminated intravascular coagulation (DIC) or malaria-related liver disorders. Malaria hepatopathy is a term that is often used to describe hepatocytic dysfunction in severe malaria, although inflammation does not occur in the liver parenchyma.  Malaria hepatopathy also characterized by a rise in serum bilirubin along with the rise in serum glutamate pyruvate trasnaminase levels. This two condition are similar but must be distinguished because of different treatment required.
ISSN:1411-4801
2302-8181