DNA damage in children with β-thalassemia minor: genotoxicity assessment by comet assay
Background. In transfusion-dependent forms of β-thalassemia, chronic anemia and iron overload lead to the development of oxidative stress-related DNA damage. In β-thalassemia minor (β-Tm), oxidative stress resulting from an unbalanced globin chain ratio has been documented, even in the absence of a...
Saved in:
| Main Authors: | Deniz Menderes, Esra Emerce, Tayfun Göktaş, Gonca Çakmak, Deniz Aslan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hacettepe University Institute of Child Health
2025-02-01
|
| Series: | The Turkish Journal of Pediatrics |
| Subjects: | |
| Online Access: | https://turkjpediatr.org/article/view/4567 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
genotoxicity produced in the epithelial cells of the oral cavity and Comet assay in urinary tract of workers in aluminum factories
by: Sarab Dalaf Khalaf, et al.
Published: (2020-06-01) -
Evaluation of the Antigenotoxic Effect of Quercetin Against Antiepileptic Drug Genotoxicity by Comet Analysis
by: Fadime Canbolat, et al.
Published: (2023-12-01) -
Evaluation of the Genotoxicity and Cytotoxicity of Bioceramic Endodontic Sealers in HepG2 and V79 Cell Lines: An In Vitro Study Using the Comet and Micronucleus Assays
by: Antonija Tadin, et al.
Published: (2025-05-01) -
Capability of Vitamin E as a Radioprotector in Suppressing DNA Damage Determined with Comet Assay
by: Darlina Darlina, et al.
Published: (2017-07-01) -
Use of cryopreserved whole blood samples in the Comet assay for detection of DNA damage in human population studies
by: K.L. Cooper, et al.
Published: (2025-12-01)