A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case Report
Desmoid tumors are a rare entity, especially in the pediatric population. There are no reports of such a tumor in newborns. They are associated with high rates of morbidity and mortality, even though they are benign soft tissue tumors. This is due to them exhibiting locally aggressive growth with th...
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2025-01-01
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| author | Irina Maria Margarint Tammam Youssef Cristina Filip Ana-Mihaela Bizubac Alexandru Popescu Iulian Rotaru Olguta Untaru Stefan Manolache Vlad Anton Iliescu Radu Vladareanu |
| author_facet | Irina Maria Margarint Tammam Youssef Cristina Filip Ana-Mihaela Bizubac Alexandru Popescu Iulian Rotaru Olguta Untaru Stefan Manolache Vlad Anton Iliescu Radu Vladareanu |
| author_sort | Irina Maria Margarint |
| collection | DOAJ |
| description | Desmoid tumors are a rare entity, especially in the pediatric population. There are no reports of such a tumor in newborns. They are associated with high rates of morbidity and mortality, even though they are benign soft tissue tumors. This is due to them exhibiting locally aggressive growth with the compression or invasion of adjacent structures. Abdominal localization is most commonly reported, although there are reports of mediastinal desmoid tumors. We present the case of a 6-day male patient with a mediastinal desmoid tumor that led to severe aortic coarctation with hemodynamic instability. The tumor also compressed the left pulmonary artery and obstructed the left main bronchus. The initial management consisted of successful emergency surgery with partial resection of the tumor mass and coarctation repair. In the postoperative setting, the patient evolved with severe respiratory dysfunction which was managed with tracheostomy, allowing weaning the child from the mechanical ventilation one month after surgery, along with chemotherapy. We also review the literature, focusing on the management of desmoid tumors. |
| format | Article |
| id | doaj-art-09ce2028bdf645198cb055ddaa4631a3 |
| institution | Kabale University |
| issn | 2075-1729 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj-art-09ce2028bdf645198cb055ddaa4631a32025-01-24T13:38:53ZengMDPI AGLife2075-17292025-01-0115112310.3390/life15010123A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case ReportIrina Maria Margarint0Tammam Youssef1Cristina Filip2Ana-Mihaela Bizubac3Alexandru Popescu4Iulian Rotaru5Olguta Untaru6Stefan Manolache7Vlad Anton Iliescu8Radu Vladareanu9Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Cardiac Surgery, Emergency Clinical Hospital for Children “Maria Skłodowska Curie”, 077120 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania“Marie S. Curie Children’s Emergency Hospital” Bucharest, Neonatal Intensive Care Unit, 20 Constantin Brancoveanu Street, District 4, 041451 Bucharest, RomaniaDepartment of Cardiac Surgery, Emergency Clinical Hospital for Children “Maria Skłodowska Curie”, 077120 Bucharest, RomaniaDepartment of Cardiac Surgery, Emergency Clinical Hospital for Children “Maria Skłodowska Curie”, 077120 Bucharest, RomaniaDepartment of Cardiac Surgery, Emergency Clinical Hospital for Children “Maria Skłodowska Curie”, 077120 Bucharest, Romania“Marie S. Curie Children’s Emergency Hospital” Bucharest, Neonatal Intensive Care Unit, 20 Constantin Brancoveanu Street, District 4, 041451 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDesmoid tumors are a rare entity, especially in the pediatric population. There are no reports of such a tumor in newborns. They are associated with high rates of morbidity and mortality, even though they are benign soft tissue tumors. This is due to them exhibiting locally aggressive growth with the compression or invasion of adjacent structures. Abdominal localization is most commonly reported, although there are reports of mediastinal desmoid tumors. We present the case of a 6-day male patient with a mediastinal desmoid tumor that led to severe aortic coarctation with hemodynamic instability. The tumor also compressed the left pulmonary artery and obstructed the left main bronchus. The initial management consisted of successful emergency surgery with partial resection of the tumor mass and coarctation repair. In the postoperative setting, the patient evolved with severe respiratory dysfunction which was managed with tracheostomy, allowing weaning the child from the mechanical ventilation one month after surgery, along with chemotherapy. We also review the literature, focusing on the management of desmoid tumors.https://www.mdpi.com/2075-1729/15/1/123desmoid tumoraortic coarctationnewbornrespiratory failure |
| spellingShingle | Irina Maria Margarint Tammam Youssef Cristina Filip Ana-Mihaela Bizubac Alexandru Popescu Iulian Rotaru Olguta Untaru Stefan Manolache Vlad Anton Iliescu Radu Vladareanu A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case Report Life desmoid tumor aortic coarctation newborn respiratory failure |
| title | A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case Report |
| title_full | A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case Report |
| title_fullStr | A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case Report |
| title_full_unstemmed | A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case Report |
| title_short | A Rare Case of Neonatal Desmoid Tumor Leading to Severe Aortic Coarctation: Review of Literature and Case Report |
| title_sort | rare case of neonatal desmoid tumor leading to severe aortic coarctation review of literature and case report |
| topic | desmoid tumor aortic coarctation newborn respiratory failure |
| url | https://www.mdpi.com/2075-1729/15/1/123 |
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