Recommendations on Describing the Requirements for Microbiological Quality and Sterility of Medicinal Products

The paper presents recommendations on describing analytical procedures for evaluation of medicinal products in terms of sterility and microbiological quality in accordance with the State Pharmacopoeia of the Russian Federation and the Pharmacopoeia of the EAEU. These quality attributes should be cov...

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Main Author: O. V. Gunar
Format: Article
Language:Russian
Published: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2022-07-01
Series:Регуляторные исследования и экспертиза лекарственных средств
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Online Access:https://www.vedomostincesmp.ru/jour/article/view/435
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author O. V. Gunar
author_facet O. V. Gunar
author_sort O. V. Gunar
collection DOAJ
description The paper presents recommendations on describing analytical procedures for evaluation of medicinal products in terms of sterility and microbiological quality in accordance with the State Pharmacopoeia of the Russian Federation and the Pharmacopoeia of the EAEU. These quality attributes should be covered in Product specification files for any medicinal product. The paper describes specific considerations for preparation of the corresponding sections of the Russian or EAEU Product specification files. It is necessary to provide and justify quality requirements, refer to or describe the recommended analytical procedure and indicate differences, if any, from the standard one. Standardisation of the approach to microbiological quality control of medicinal products will allow analysts to accurately perform the tests, get reliable results and ensure the safety of medicinal products.
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institution Kabale University
issn 3034-3062
3034-3453
language Russian
publishDate 2022-07-01
publisher Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’)
record_format Article
series Регуляторные исследования и экспертиза лекарственных средств
spelling doaj-art-09c467651bbf4c0a9fbb0cc3cc7b25b42025-08-20T03:40:14ZrusFederal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’)Регуляторные исследования и экспертиза лекарственных средств3034-30623034-34532022-07-0112212012310.30895/1991-2919-2022-12-2-120-123315Recommendations on Describing the Requirements for Microbiological Quality and Sterility of Medicinal ProductsO. V. Gunar0Scientific Centre for Expert Evaluation of Medicinal ProductsThe paper presents recommendations on describing analytical procedures for evaluation of medicinal products in terms of sterility and microbiological quality in accordance with the State Pharmacopoeia of the Russian Federation and the Pharmacopoeia of the EAEU. These quality attributes should be covered in Product specification files for any medicinal product. The paper describes specific considerations for preparation of the corresponding sections of the Russian or EAEU Product specification files. It is necessary to provide and justify quality requirements, refer to or describe the recommended analytical procedure and indicate differences, if any, from the standard one. Standardisation of the approach to microbiological quality control of medicinal products will allow analysts to accurately perform the tests, get reliable results and ensure the safety of medicinal products.https://www.vedomostincesmp.ru/jour/article/view/435medicinal productsqualitysterilitymicrobiological quality
spellingShingle O. V. Gunar
Recommendations on Describing the Requirements for Microbiological Quality and Sterility of Medicinal Products
Регуляторные исследования и экспертиза лекарственных средств
medicinal products
quality
sterility
microbiological quality
title Recommendations on Describing the Requirements for Microbiological Quality and Sterility of Medicinal Products
title_full Recommendations on Describing the Requirements for Microbiological Quality and Sterility of Medicinal Products
title_fullStr Recommendations on Describing the Requirements for Microbiological Quality and Sterility of Medicinal Products
title_full_unstemmed Recommendations on Describing the Requirements for Microbiological Quality and Sterility of Medicinal Products
title_short Recommendations on Describing the Requirements for Microbiological Quality and Sterility of Medicinal Products
title_sort recommendations on describing the requirements for microbiological quality and sterility of medicinal products
topic medicinal products
quality
sterility
microbiological quality
url https://www.vedomostincesmp.ru/jour/article/view/435
work_keys_str_mv AT ovgunar recommendationsondescribingtherequirementsformicrobiologicalqualityandsterilityofmedicinalproducts