Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit‐stand maneuvers and spontaneous rest
Abstract The cardiac baroreflex regulates arterial pressure via autonomic heart rate control. While sit‐stand maneuvers (SSM) have been used to assess baroreflex sensitivity (BRS), they may be impractical for physically immobile individuals. This study examined cardiac BRS during repeated handgrip e...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-05-01
|
| Series: | Physiological Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.14814/phy2.70352 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850277087367135232 |
|---|---|
| author | Wenxing Qin Marina Fukuie Daisuke Hoshi Shoya Mori Tsubasa Tomoto Shigehiko Ogoh Jun Sugawara Takashi Tarumi |
| author_facet | Wenxing Qin Marina Fukuie Daisuke Hoshi Shoya Mori Tsubasa Tomoto Shigehiko Ogoh Jun Sugawara Takashi Tarumi |
| author_sort | Wenxing Qin |
| collection | DOAJ |
| description | Abstract The cardiac baroreflex regulates arterial pressure via autonomic heart rate control. While sit‐stand maneuvers (SSM) have been used to assess baroreflex sensitivity (BRS), they may be impractical for physically immobile individuals. This study examined cardiac BRS during repeated handgrip exercise (RHE) compared to SSM and spontaneous rest. Twenty participants (10 females) performed 5‐min RHE and SSM at 0.10 and 0.05 Hz in random order after spontaneous rest. Cardiac BRS was calculated using transfer function analysis (BRSTFA) and the sequence method (BRSSM) in low (LF: 0.05–0.15 Hz) and very low (VLF: 0.02–0.07 Hz) frequencies. Power spectral density (PSD) quantified systolic blood pressure (SBP) and R‐R interval (RRI) oscillations. Compared to rest, 0.10 and 0.05 Hz RHE significantly increased SBP and RRI PSDs, with the highest values observed during SSM in both frequencies. RHE significantly increased LF and VLF BRSTFA coherence by 132% and 142%, while SSM increased them by 144% and 209%. Regardless of analytical methods, BRS remained unchanged during RHE compared to rest, but it significantly decreased during 0.10 Hz SSM, which correlated with increased heart rate. These findings suggest that RHE improves BRSTFA estimation via increased coherence, whereas reduced BRS during SSM suggests baroreflex resetting. |
| format | Article |
| id | doaj-art-09bbd4bb34b542ca9ca828a7546aee74 |
| institution | OA Journals |
| issn | 2051-817X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Physiological Reports |
| spelling | doaj-art-09bbd4bb34b542ca9ca828a7546aee742025-08-20T01:50:00ZengWileyPhysiological Reports2051-817X2025-05-01139n/an/a10.14814/phy2.70352Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit‐stand maneuvers and spontaneous restWenxing Qin0Marina Fukuie1Daisuke Hoshi2Shoya Mori3Tsubasa Tomoto4Shigehiko Ogoh5Jun Sugawara6Takashi Tarumi7Institute of Health and Sport Sciences University of Tsukuba Tsukuba Ibaraki JapanHuman Informatics and Interaction Research Institute National Institute of Advanced Industrial Science and Technology Tsukuba Ibaraki JapanHuman Informatics and Interaction Research Institute National Institute of Advanced Industrial Science and Technology Tsukuba Ibaraki JapanInstitute of Health and Sport Sciences University of Tsukuba Tsukuba Ibaraki JapanHuman Informatics and Interaction Research Institute National Institute of Advanced Industrial Science and Technology Tsukuba Ibaraki JapanDepartment of Biomedical Engineering Toyo University Saitama JapanInstitute of Health and Sport Sciences University of Tsukuba Tsukuba Ibaraki JapanInstitute of Health and Sport Sciences University of Tsukuba Tsukuba Ibaraki JapanAbstract The cardiac baroreflex regulates arterial pressure via autonomic heart rate control. While sit‐stand maneuvers (SSM) have been used to assess baroreflex sensitivity (BRS), they may be impractical for physically immobile individuals. This study examined cardiac BRS during repeated handgrip exercise (RHE) compared to SSM and spontaneous rest. Twenty participants (10 females) performed 5‐min RHE and SSM at 0.10 and 0.05 Hz in random order after spontaneous rest. Cardiac BRS was calculated using transfer function analysis (BRSTFA) and the sequence method (BRSSM) in low (LF: 0.05–0.15 Hz) and very low (VLF: 0.02–0.07 Hz) frequencies. Power spectral density (PSD) quantified systolic blood pressure (SBP) and R‐R interval (RRI) oscillations. Compared to rest, 0.10 and 0.05 Hz RHE significantly increased SBP and RRI PSDs, with the highest values observed during SSM in both frequencies. RHE significantly increased LF and VLF BRSTFA coherence by 132% and 142%, while SSM increased them by 144% and 209%. Regardless of analytical methods, BRS remained unchanged during RHE compared to rest, but it significantly decreased during 0.10 Hz SSM, which correlated with increased heart rate. These findings suggest that RHE improves BRSTFA estimation via increased coherence, whereas reduced BRS during SSM suggests baroreflex resetting.https://doi.org/10.14814/phy2.70352baroreflexexercisehandgripsequence methodsit‐standtransfer function |
| spellingShingle | Wenxing Qin Marina Fukuie Daisuke Hoshi Shoya Mori Tsubasa Tomoto Shigehiko Ogoh Jun Sugawara Takashi Tarumi Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit‐stand maneuvers and spontaneous rest Physiological Reports baroreflex exercise handgrip sequence method sit‐stand transfer function |
| title | Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit‐stand maneuvers and spontaneous rest |
| title_full | Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit‐stand maneuvers and spontaneous rest |
| title_fullStr | Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit‐stand maneuvers and spontaneous rest |
| title_full_unstemmed | Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit‐stand maneuvers and spontaneous rest |
| title_short | Cardiac baroreflex sensitivity during repeated handgrip exercise: Comparisons with sit‐stand maneuvers and spontaneous rest |
| title_sort | cardiac baroreflex sensitivity during repeated handgrip exercise comparisons with sit stand maneuvers and spontaneous rest |
| topic | baroreflex exercise handgrip sequence method sit‐stand transfer function |
| url | https://doi.org/10.14814/phy2.70352 |
| work_keys_str_mv | AT wenxingqin cardiacbaroreflexsensitivityduringrepeatedhandgripexercisecomparisonswithsitstandmaneuversandspontaneousrest AT marinafukuie cardiacbaroreflexsensitivityduringrepeatedhandgripexercisecomparisonswithsitstandmaneuversandspontaneousrest AT daisukehoshi cardiacbaroreflexsensitivityduringrepeatedhandgripexercisecomparisonswithsitstandmaneuversandspontaneousrest AT shoyamori cardiacbaroreflexsensitivityduringrepeatedhandgripexercisecomparisonswithsitstandmaneuversandspontaneousrest AT tsubasatomoto cardiacbaroreflexsensitivityduringrepeatedhandgripexercisecomparisonswithsitstandmaneuversandspontaneousrest AT shigehikoogoh cardiacbaroreflexsensitivityduringrepeatedhandgripexercisecomparisonswithsitstandmaneuversandspontaneousrest AT junsugawara cardiacbaroreflexsensitivityduringrepeatedhandgripexercisecomparisonswithsitstandmaneuversandspontaneousrest AT takashitarumi cardiacbaroreflexsensitivityduringrepeatedhandgripexercisecomparisonswithsitstandmaneuversandspontaneousrest |