Efficacy, safety and single-cell analysis of neoadjuvant immunochemotherapy in locally advanced oral squamous cell carcinoma: a phase II trial

Efficacy, safety and single-cell analysis of neoadjuvant immunochemotherapy in locally advanced oral squamous cell carcinoma: a phase II trial

Abstract The clinical activity of neoadjuvant immunochemotherapy (NAIC) for treating locally advanced oral squamous cell carcinoma (LA-OSCC) remains uncertain. This single-arm, phase II trial (ChiCTR2200066119) tested 2 cycles of NAIC with camrelizumab plus nab-paclitaxel and cisplatin in LA-OSCC pa...

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Main Authors: Zhongzheng Xiang, Xiaoyuan Wei, Zhuoyuan Zhang, Yueyang Tang, Linyan Chen, Chenfeng Tan, Yuanyuan Zeng, Jun Wang, Guile Zhao, Zelei Dai, Mingmin He, Ningyue Xu, Chunjie Li, Yi Li, Lei Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59004-w
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