Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

<h4>Background</h4>Human African trypanosomiasis (HAT or sleeping sickness) is caused by the parasite Trypanosoma brucei sspp. The disease has two stages, a haemolymphatic stage after the bite of an infected tsetse fly, followed by a central nervous system stage where the parasite penetr...

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Main Authors: Lisa Sanderson, Marcelo da Silva, Gayathri N Sekhar, Rachel C Brown, Hollie Burrell-Saward, Mehmet Fidanboylu, Bo Liu, Lea Ann Dailey, Cécile A Dreiss, Chris Lorenz, Mark Christie, Shanta J Persaud, Vanessa Yardley, Simon L Croft, Margarita Valero, Sarah A Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0009276&type=printable
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