Viral Infection in Renal Transplant Recipients
Viruses are among the most common causes of opportunistic infection after transplantation. The risk for viral infection is a function of the specific virus encountered, the intensity of immune suppression used to prevent graft rejection, and other host factors governing susceptibility. Although cyto...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/820621 |
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| _version_ | 1832551091178307584 |
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| author | Jovana Cukuranovic Sladjana Ugrenovic Ivan Jovanovic Milan Visnjic Vladisav Stefanovic |
| author_facet | Jovana Cukuranovic Sladjana Ugrenovic Ivan Jovanovic Milan Visnjic Vladisav Stefanovic |
| author_sort | Jovana Cukuranovic |
| collection | DOAJ |
| description | Viruses are among the most common causes of opportunistic infection after transplantation. The risk for viral infection is a function of the specific virus encountered, the intensity of immune suppression used to prevent graft rejection, and other host factors governing susceptibility. Although cytomegalovirus is the most common opportunistic pathogen seen in transplant recipients, numerous other viruses have also affected outcomes. In some cases, preventive measures such as pretransplant screening, prophylactic antiviral therapy, or posttransplant viral monitoring may limit the impact of these infections. Recent advances in laboratory monitoring and antiviral therapy have improved outcomes. Studies of viral latency, reactivation, and the cellular effects of viral infection will provide clues for future strategies in prevention and treatment of viral infections. This paper will summarize the major viral infections seen following transplant and discuss strategies for prevention and management of these potential pathogens. |
| format | Article |
| id | doaj-art-09b06e330c614ac094190f2e048a9bae |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-09b06e330c614ac094190f2e048a9bae2025-02-03T06:04:57ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/820621820621Viral Infection in Renal Transplant RecipientsJovana Cukuranovic0Sladjana Ugrenovic1Ivan Jovanovic2Milan Visnjic3Vladisav Stefanovic4Faculty of Medicine, University of Nis, 18000 Nis, SerbiaFaculty of Medicine, University of Nis, 18000 Nis, SerbiaFaculty of Medicine, University of Nis, 18000 Nis, SerbiaFaculty of Medicine, University of Nis, 18000 Nis, SerbiaFaculty of Medicine, University of Nis, 18000 Nis, SerbiaViruses are among the most common causes of opportunistic infection after transplantation. The risk for viral infection is a function of the specific virus encountered, the intensity of immune suppression used to prevent graft rejection, and other host factors governing susceptibility. Although cytomegalovirus is the most common opportunistic pathogen seen in transplant recipients, numerous other viruses have also affected outcomes. In some cases, preventive measures such as pretransplant screening, prophylactic antiviral therapy, or posttransplant viral monitoring may limit the impact of these infections. Recent advances in laboratory monitoring and antiviral therapy have improved outcomes. Studies of viral latency, reactivation, and the cellular effects of viral infection will provide clues for future strategies in prevention and treatment of viral infections. This paper will summarize the major viral infections seen following transplant and discuss strategies for prevention and management of these potential pathogens.http://dx.doi.org/10.1100/2012/820621 |
| spellingShingle | Jovana Cukuranovic Sladjana Ugrenovic Ivan Jovanovic Milan Visnjic Vladisav Stefanovic Viral Infection in Renal Transplant Recipients The Scientific World Journal |
| title | Viral Infection in Renal Transplant Recipients |
| title_full | Viral Infection in Renal Transplant Recipients |
| title_fullStr | Viral Infection in Renal Transplant Recipients |
| title_full_unstemmed | Viral Infection in Renal Transplant Recipients |
| title_short | Viral Infection in Renal Transplant Recipients |
| title_sort | viral infection in renal transplant recipients |
| url | http://dx.doi.org/10.1100/2012/820621 |
| work_keys_str_mv | AT jovanacukuranovic viralinfectioninrenaltransplantrecipients AT sladjanaugrenovic viralinfectioninrenaltransplantrecipients AT ivanjovanovic viralinfectioninrenaltransplantrecipients AT milanvisnjic viralinfectioninrenaltransplantrecipients AT vladisavstefanovic viralinfectioninrenaltransplantrecipients |