Combination of genetic studies and animal modeling proposes TMPRSS9 as a candidate gene for serum K+ variations
Abstract A candidate gene association analysis identified TMPRSS9 as gene for potassium sensitivity in women. To validate this finding, constitutive and conditional Tmprss9 knockout mice were generated and subjected to dietary K+ deprivation and K+ loading. Interestingly, mouse renal Tmprss9 gene ex...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-11106-7 |
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