Chitosan Nanoparticles Enhance the Antiproliferative Effect of Lapachol in Urothelial Carcinoma Cell Lines

Chitosan Nanoparticles Enhance the Antiproliferative Effect of Lapachol in Urothelial Carcinoma Cell Lines

<b>Backgroud/Objectives:</b> Lapachol is a naturally occurring prenylated naphthoquinone with antiproliferative effects. However, its clinical application remains limited due to several factors, including poor water solubility, low bioavailability, and adverse effects. The development of...

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Main Authors: Tatiane Roquete Amparo, Kamila de Fátima da Anunciação, Tamires Cunha Almeida, Lucas Resende Dutra Sousa, Viviane Flores Xavier, Janaína Brandão Seibert, Ana Paula Moreira Barboza, Paula Melo de Abreu Vieira, Orlando David Henrique dos Santos, Glenda Nicioli da Silva, Geraldo Célio Brandão
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Pharmaceutics
Subjects:
lapachol
bladder cancer
nanoemulsion
nanospheres
chitosan
Online Access:https://www.mdpi.com/1999-4923/17/7/868
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