Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link?
Advanced carotid disease is known to be associated with symptomatic cerebrovascular diseases, such as stroke or transient ischemic attack (TIA), as well as with poststroke cognitive impairment. However, cognitive decline often occurs in patients with advanced carotid stenosis without clinically evid...
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Format: | Article |
Language: | English |
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Wiley
2012-01-01
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Series: | Stroke Research and Treatment |
Online Access: | http://dx.doi.org/10.1155/2012/981416 |
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author | Irena Martinić-Popović Arijana Lovrenčić-Huzjan Vida Demarin |
author_facet | Irena Martinić-Popović Arijana Lovrenčić-Huzjan Vida Demarin |
author_sort | Irena Martinić-Popović |
collection | DOAJ |
description | Advanced carotid disease is known to be associated with symptomatic cerebrovascular diseases, such as stroke or transient ischemic attack (TIA), as well as with poststroke cognitive impairment. However, cognitive decline often occurs in patients with advanced carotid stenosis without clinically evident stroke or TIA, so it is also suspected to be an independent risk factor for dementia. Neurosonological methods enable simple and noninvasive assessment of carotid stenosis in patients at risk of advanced atherosclerosis. Cognitive status in patients diagnosed with advanced carotid stenosis is routinely not taken into consideration, although if cognitive impairment is present, such patients should probably be called symptomatic. In this paper, we discuss results of some most important studies that investigated cognitive status of patients with asymptomatic advanced carotid disease and possible mechanisms involved in the causal relationship between asymptomatic advanced carotid disease and cognitive decline. |
format | Article |
id | doaj-art-09a93d86720148cc988a0cd8799c98eb |
institution | Kabale University |
issn | 2090-8105 2042-0056 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Stroke Research and Treatment |
spelling | doaj-art-09a93d86720148cc988a0cd8799c98eb2025-02-03T05:45:51ZengWileyStroke Research and Treatment2090-81052042-00562012-01-01201210.1155/2012/981416981416Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link?Irena Martinić-Popović0Arijana Lovrenčić-Huzjan1Vida Demarin2University Department of Neurology, Sestre Milosrdnice University Hospital Center, 10000 Zagreb, CroatiaUniversity Department of Neurology, Sestre Milosrdnice University Hospital Center, 10000 Zagreb, CroatiaUniversity Department of Neurology, Sestre Milosrdnice University Hospital Center, 10000 Zagreb, CroatiaAdvanced carotid disease is known to be associated with symptomatic cerebrovascular diseases, such as stroke or transient ischemic attack (TIA), as well as with poststroke cognitive impairment. However, cognitive decline often occurs in patients with advanced carotid stenosis without clinically evident stroke or TIA, so it is also suspected to be an independent risk factor for dementia. Neurosonological methods enable simple and noninvasive assessment of carotid stenosis in patients at risk of advanced atherosclerosis. Cognitive status in patients diagnosed with advanced carotid stenosis is routinely not taken into consideration, although if cognitive impairment is present, such patients should probably be called symptomatic. In this paper, we discuss results of some most important studies that investigated cognitive status of patients with asymptomatic advanced carotid disease and possible mechanisms involved in the causal relationship between asymptomatic advanced carotid disease and cognitive decline.http://dx.doi.org/10.1155/2012/981416 |
spellingShingle | Irena Martinić-Popović Arijana Lovrenčić-Huzjan Vida Demarin Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link? Stroke Research and Treatment |
title | Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link? |
title_full | Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link? |
title_fullStr | Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link? |
title_full_unstemmed | Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link? |
title_short | Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link? |
title_sort | advanced asymptomatic carotid disease and cognitive impairment an understated link |
url | http://dx.doi.org/10.1155/2012/981416 |
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