Anaesthetic management of liver transplantation in patients with fulminant hepatic failure
Acute Liver Failure (ALF) is associated with rapidly progressive multiorgan failure and may even lead to death. Although liver transplantation (LT) has emerged as the only viable treatment option, there are many challenges associated with LT. The literature available from developed countries mainly...
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| Format: | Article |
| Language: | English |
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Pakistan Medical Association
2024-12-01
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| Series: | Journal of the Pakistan Medical Association |
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| Online Access: | https://jpma.org.pk/index.php/public_html/article/view/9055 |
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| author | Saad Ahmed Naved Sadiq Shoukat Ali Parpia |
| author_facet | Saad Ahmed Naved Sadiq Shoukat Ali Parpia |
| author_sort | Saad Ahmed Naved |
| collection | DOAJ |
| description |
Acute Liver Failure (ALF) is associated with rapidly progressive multiorgan failure and may even lead to death. Although liver transplantation (LT) has emerged as the only viable treatment option, there are many challenges associated with LT. The literature available from developed countries mainly focuses on the prognosis of ALF with limited focus on the anaesthetic management of LT. In the developing world particularly, the facility and experience of LT is relatively new. This case report presents the first case from Pakistan regarding the anaesthesia management of ALF. It discusses the management of a 46-year-old female who underwent emergency LT which includes initiation of Total Intravenous Anaesthesia, steps to reduce intra-cranial pressure, continuous Renal Replacement Therapy, and correction of coagulopathy using thromboelastography. To conclude, a holistic understanding of pre, intra, and post-operative anaesthetic management of liver transplantation requires a multi-disciplinary team management and can significantly improve the survival rates.
Keywords: Liver Transplant, Anaesthesia, Liver Failure.
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| format | Article |
| id | doaj-art-09a7254d36d741de87b27e8fa0a5e151 |
| institution | Kabale University |
| issn | 0030-9982 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Pakistan Medical Association |
| record_format | Article |
| series | Journal of the Pakistan Medical Association |
| spelling | doaj-art-09a7254d36d741de87b27e8fa0a5e1512025-08-20T03:39:56ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822024-12-0175110.47391/JPMA.9055Anaesthetic management of liver transplantation in patients with fulminant hepatic failureSaad Ahmed Naved0Sadiq Shoukat Ali Parpia1Department of Anaesthesia, Shifa International Hospital, Islamabad, PakistanDepartment of Anaesthesia, Shifa International Hospital, Islamabad, Pakistan Acute Liver Failure (ALF) is associated with rapidly progressive multiorgan failure and may even lead to death. Although liver transplantation (LT) has emerged as the only viable treatment option, there are many challenges associated with LT. The literature available from developed countries mainly focuses on the prognosis of ALF with limited focus on the anaesthetic management of LT. In the developing world particularly, the facility and experience of LT is relatively new. This case report presents the first case from Pakistan regarding the anaesthesia management of ALF. It discusses the management of a 46-year-old female who underwent emergency LT which includes initiation of Total Intravenous Anaesthesia, steps to reduce intra-cranial pressure, continuous Renal Replacement Therapy, and correction of coagulopathy using thromboelastography. To conclude, a holistic understanding of pre, intra, and post-operative anaesthetic management of liver transplantation requires a multi-disciplinary team management and can significantly improve the survival rates. Keywords: Liver Transplant, Anaesthesia, Liver Failure. https://jpma.org.pk/index.php/public_html/article/view/9055Liver TransplantAnaesthesiaLiver Failure |
| spellingShingle | Saad Ahmed Naved Sadiq Shoukat Ali Parpia Anaesthetic management of liver transplantation in patients with fulminant hepatic failure Journal of the Pakistan Medical Association Liver Transplant Anaesthesia Liver Failure |
| title | Anaesthetic management of liver transplantation in patients with fulminant hepatic failure |
| title_full | Anaesthetic management of liver transplantation in patients with fulminant hepatic failure |
| title_fullStr | Anaesthetic management of liver transplantation in patients with fulminant hepatic failure |
| title_full_unstemmed | Anaesthetic management of liver transplantation in patients with fulminant hepatic failure |
| title_short | Anaesthetic management of liver transplantation in patients with fulminant hepatic failure |
| title_sort | anaesthetic management of liver transplantation in patients with fulminant hepatic failure |
| topic | Liver Transplant Anaesthesia Liver Failure |
| url | https://jpma.org.pk/index.php/public_html/article/view/9055 |
| work_keys_str_mv | AT saadahmednaved anaestheticmanagementoflivertransplantationinpatientswithfulminanthepaticfailure AT sadiqshoukataliparpia anaestheticmanagementoflivertransplantationinpatientswithfulminanthepaticfailure |