Prevalence, determinants, and complications of adolescent pregnancy: an umbrella review of systematic reviews and meta-analysesAJOG Global Reports at a Glance

OBJECTIVE: This study aimed to assess the magnitude, determinants, and outcomes of adolescent pregnancy by combining data from previous systematic reviews and meta-analyses. DATA SOURCES: Online databases. STUDY ELIGIBILITY CRITERIA: Systematic Review and Meta-analysis. METHODS: Using the Preferred...

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Main Authors: Biruk Beletew Abate, Ashenafi Kibret Sendekie, MSc, Addis Wondimagegn Alamaw, MSc, Kindie Mekuria Tegegne, MSc, Tegene Atamenta Kitaw, MSc, Molla Azmeraw Bizuayehu, MSc, Amare Kassaw, MSc, Gizachew Yilak, MSc, Alemu Birara Zemariam, MSc, Befkad Derese Tilahun, MSc
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:AJOG Global Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666577825000024
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author Biruk Beletew Abate
Ashenafi Kibret Sendekie, MSc
Addis Wondimagegn Alamaw, MSc
Kindie Mekuria Tegegne, MSc
Tegene Atamenta Kitaw, MSc
Molla Azmeraw Bizuayehu, MSc
Amare Kassaw, MSc
Gizachew Yilak, MSc
Alemu Birara Zemariam, MSc
Befkad Derese Tilahun, MSc
author_facet Biruk Beletew Abate
Ashenafi Kibret Sendekie, MSc
Addis Wondimagegn Alamaw, MSc
Kindie Mekuria Tegegne, MSc
Tegene Atamenta Kitaw, MSc
Molla Azmeraw Bizuayehu, MSc
Amare Kassaw, MSc
Gizachew Yilak, MSc
Alemu Birara Zemariam, MSc
Befkad Derese Tilahun, MSc
author_sort Biruk Beletew Abate
collection DOAJ
description OBJECTIVE: This study aimed to assess the magnitude, determinants, and outcomes of adolescent pregnancy by combining data from previous systematic reviews and meta-analyses. DATA SOURCES: Online databases. STUDY ELIGIBILITY CRITERIA: Systematic Review and Meta-analysis. METHODS: Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, PubMed, Embase, Scopus, Web of Sciences, Cochrane Database of Systematic Reviews, Scopus, and Google Scholar, which reported the magnitude, predictors, and/or outcomes of adolescent pregnancy, were searched. The quality of the included studies was assessed using the Assessment of Multiple Systematic Reviews. A weighted inverse variance random-effects model was used to determine the pooled estimates. In addition, subgroup heterogeneity, publication bias, and sensitivity were assessed. RESULTS: A total of 14 systematic reviews and meta-analyses involving 677,431 participants were included in the final analysis of this umbrella review. The pooled prevalence of adolescent pregnancy from global systematic reviews and meta-analyses was found to be 17.90 (95% confidence interval, 12.25–23.54). Level of education (adjusted odds ratio ranging from 1.40 to 9.07), socioeconomic status (lower: adjusted odds ratio ranging from 1.13 to 3.81), residency (rural: adjusted odds ratio ranging from 1.80 to 3.60), abuse (adjusted odds ratio ranging from 2.21 to 3.83), marital status (married: adjusted odds ratio ranging from 1.27 to 6.02), and contraceptive use (no: adjusted odds ratio ranging from 0.19 to 3.53) were identified as predictors of adolescent pregnancy. Anemia (adjusted odds ratio, 1.49; 95% confidence interval, 0.29–1.69; I2= 91.7%), stillbirth (adjusted odds ratio, 1.71; 95% confidence interval, 0.24–3.17; I2= 61.3%), preeclampsia/eclampsia, (adjusted odds ratio, 1.63; 95% confidence interval, 0.72–2.55), preterm birth (adjusted odds ratio, 1.90; 95% confidence interval, 1.36–2.40), and low birthweight (adjusted odds ratio, 1.46; 95% confidence interval, 1.25–1.66) were found to be significant complications of adolescent pregnancy in a global context. CONCLUSION: The prevalence of adolescent pregnancy varied significantly across previous systematic reviews and meta-analyses. The key determinants identified included low socioeconomic status, rural residency, a history of abuse, early marriage, and no contraceptive use. The complications associated with adolescent pregnancy included anemia, stillbirth, preeclampsia/eclampsia, preterm birth, and low birthweight. To reduce the burden of adolescent pregnancy, collaborative efforts are required from global, regional, and local stakeholders, such as policymakers and reproductive health program planners, through health education and training that focus on the most vulnerable populations.
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spelling doaj-art-09a24af091da4bec9cbc378c4868cfa82025-08-20T03:17:47ZengElsevierAJOG Global Reports2666-57782025-02-015110044110.1016/j.xagr.2025.100441Prevalence, determinants, and complications of adolescent pregnancy: an umbrella review of systematic reviews and meta-analysesAJOG Global Reports at a GlanceBiruk Beletew Abate0Ashenafi Kibret Sendekie, MSc1Addis Wondimagegn Alamaw, MSc2Kindie Mekuria Tegegne, MSc3Tegene Atamenta Kitaw, MSc4Molla Azmeraw Bizuayehu, MSc5Amare Kassaw, MSc6Gizachew Yilak, MSc7Alemu Birara Zemariam, MSc8Befkad Derese Tilahun, MSc9School of Population Health, Curtin University, Perth, Australia (Abate); College of Medicine and Health Sciences, Woldia University, Woldia, Ethiopia (Abate); Corresponding author: Biruk Beletew Abate.Department of Clinical Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia (Sendekie); Faculty of Health Sciences, Curtin Medical School, Curtin University, Bentley, Australia (Sendekie)Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia (Alamaw, Tegegne, Kitaw, Bizuayehu, Yilak, Zemariam, and Tilahun)Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia (Alamaw, Tegegne, Kitaw, Bizuayehu, Yilak, Zemariam, and Tilahun)Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia (Alamaw, Tegegne, Kitaw, Bizuayehu, Yilak, Zemariam, and Tilahun)Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia (Alamaw, Tegegne, Kitaw, Bizuayehu, Yilak, Zemariam, and Tilahun)Department of Nursing, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia (Kassaw).Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia (Alamaw, Tegegne, Kitaw, Bizuayehu, Yilak, Zemariam, and Tilahun)Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia (Alamaw, Tegegne, Kitaw, Bizuayehu, Yilak, Zemariam, and Tilahun)Department of Nursing, College of Health Science, Woldia University, Woldia, Ethiopia (Alamaw, Tegegne, Kitaw, Bizuayehu, Yilak, Zemariam, and Tilahun)OBJECTIVE: This study aimed to assess the magnitude, determinants, and outcomes of adolescent pregnancy by combining data from previous systematic reviews and meta-analyses. DATA SOURCES: Online databases. STUDY ELIGIBILITY CRITERIA: Systematic Review and Meta-analysis. METHODS: Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, PubMed, Embase, Scopus, Web of Sciences, Cochrane Database of Systematic Reviews, Scopus, and Google Scholar, which reported the magnitude, predictors, and/or outcomes of adolescent pregnancy, were searched. The quality of the included studies was assessed using the Assessment of Multiple Systematic Reviews. A weighted inverse variance random-effects model was used to determine the pooled estimates. In addition, subgroup heterogeneity, publication bias, and sensitivity were assessed. RESULTS: A total of 14 systematic reviews and meta-analyses involving 677,431 participants were included in the final analysis of this umbrella review. The pooled prevalence of adolescent pregnancy from global systematic reviews and meta-analyses was found to be 17.90 (95% confidence interval, 12.25–23.54). Level of education (adjusted odds ratio ranging from 1.40 to 9.07), socioeconomic status (lower: adjusted odds ratio ranging from 1.13 to 3.81), residency (rural: adjusted odds ratio ranging from 1.80 to 3.60), abuse (adjusted odds ratio ranging from 2.21 to 3.83), marital status (married: adjusted odds ratio ranging from 1.27 to 6.02), and contraceptive use (no: adjusted odds ratio ranging from 0.19 to 3.53) were identified as predictors of adolescent pregnancy. Anemia (adjusted odds ratio, 1.49; 95% confidence interval, 0.29–1.69; I2= 91.7%), stillbirth (adjusted odds ratio, 1.71; 95% confidence interval, 0.24–3.17; I2= 61.3%), preeclampsia/eclampsia, (adjusted odds ratio, 1.63; 95% confidence interval, 0.72–2.55), preterm birth (adjusted odds ratio, 1.90; 95% confidence interval, 1.36–2.40), and low birthweight (adjusted odds ratio, 1.46; 95% confidence interval, 1.25–1.66) were found to be significant complications of adolescent pregnancy in a global context. CONCLUSION: The prevalence of adolescent pregnancy varied significantly across previous systematic reviews and meta-analyses. The key determinants identified included low socioeconomic status, rural residency, a history of abuse, early marriage, and no contraceptive use. The complications associated with adolescent pregnancy included anemia, stillbirth, preeclampsia/eclampsia, preterm birth, and low birthweight. To reduce the burden of adolescent pregnancy, collaborative efforts are required from global, regional, and local stakeholders, such as policymakers and reproductive health program planners, through health education and training that focus on the most vulnerable populations.http://www.sciencedirect.com/science/article/pii/S2666577825000024adolescent pregnancydeterminantsglobaloutcomesprevalenceumbrella review
spellingShingle Biruk Beletew Abate
Ashenafi Kibret Sendekie, MSc
Addis Wondimagegn Alamaw, MSc
Kindie Mekuria Tegegne, MSc
Tegene Atamenta Kitaw, MSc
Molla Azmeraw Bizuayehu, MSc
Amare Kassaw, MSc
Gizachew Yilak, MSc
Alemu Birara Zemariam, MSc
Befkad Derese Tilahun, MSc
Prevalence, determinants, and complications of adolescent pregnancy: an umbrella review of systematic reviews and meta-analysesAJOG Global Reports at a Glance
AJOG Global Reports
adolescent pregnancy
determinants
global
outcomes
prevalence
umbrella review
title Prevalence, determinants, and complications of adolescent pregnancy: an umbrella review of systematic reviews and meta-analysesAJOG Global Reports at a Glance
title_full Prevalence, determinants, and complications of adolescent pregnancy: an umbrella review of systematic reviews and meta-analysesAJOG Global Reports at a Glance
title_fullStr Prevalence, determinants, and complications of adolescent pregnancy: an umbrella review of systematic reviews and meta-analysesAJOG Global Reports at a Glance
title_full_unstemmed Prevalence, determinants, and complications of adolescent pregnancy: an umbrella review of systematic reviews and meta-analysesAJOG Global Reports at a Glance
title_short Prevalence, determinants, and complications of adolescent pregnancy: an umbrella review of systematic reviews and meta-analysesAJOG Global Reports at a Glance
title_sort prevalence determinants and complications of adolescent pregnancy an umbrella review of systematic reviews and meta analysesajog global reports at a glance
topic adolescent pregnancy
determinants
global
outcomes
prevalence
umbrella review
url http://www.sciencedirect.com/science/article/pii/S2666577825000024
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