Chemical Warfare Agents: Structure, Properties, Decontamination (Part 2)
The review is aimed at summarizing and systematizing information about various methods of deactivation of chemical warfare agents that are necessary on the battlefield, as well as in laboratories, research institutions, and facilities of production, storage, and destruction of poisonous substances....
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| Format: | Article |
| Language: | English |
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National University of Pharmacy (Kharkiv)
2024-12-01
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| Series: | Журнал органічної та фармацевтичної хімії |
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| Online Access: | https://ophcj.nuph.edu.ua/article/view/313307 |
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| author | Olexander E. Shumeiko Mykola I. Korotkikh |
| author_facet | Olexander E. Shumeiko Mykola I. Korotkikh |
| author_sort | Olexander E. Shumeiko |
| collection | DOAJ |
| description | The review is aimed at summarizing and systematizing information about various methods of deactivation of chemical warfare agents that are necessary on the battlefield, as well as in laboratories, research institutions, and facilities of production, storage, and destruction of poisonous substances. The review presents the main directions of neutralizing warfare poisonous substances, which are the most effective in the conditions of their real use. In the second part of this work, the methods of deactivating warfare poisons using nucleophilic reagents, primarily α-nucleophiles, which have high efficiency and can react as nucleophiles and as oxidants, are considered in detail. A promising area of degradation of such products is the use of supernucleophilic systems based on functionalized detergents, as well as adsorption and photocatalytic deactivation methods. The material presented above shows the importance of general knowledge about the physical and chemical properties of chemical warfare agents, the rate of their decomposition, the advantages and disadvantages of certain available technologies for their application. This review can be useful for finding new and improving known methods for decontamination of chemical warfare agents and other ecotoxicants, and protecting the environment. |
| format | Article |
| id | doaj-art-098d8a89b62846d083071da1acd875cf |
| institution | DOAJ |
| issn | 2308-8303 2518-1548 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | National University of Pharmacy (Kharkiv) |
| record_format | Article |
| series | Журнал органічної та фармацевтичної хімії |
| spelling | doaj-art-098d8a89b62846d083071da1acd875cf2025-08-20T02:57:04ZengNational University of Pharmacy (Kharkiv)Журнал органічної та фармацевтичної хімії2308-83032518-15482024-12-01223102310.24959/ophcj.24.313307Chemical Warfare Agents: Structure, Properties, Decontamination (Part 2)Olexander E. Shumeiko0https://orcid.org/0000-0001-5856-9871Mykola I. Korotkikh1https://orcid.org/0000-0003-0774-6588L. M. Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry of the National Academy of Sciences of Ukraine; Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, UkraineL. M. Litvinenko Institute of Physical-Organic Chemistry and Coal Chemistry of the National Academy of Sciences of Ukraine; Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, UkraineThe review is aimed at summarizing and systematizing information about various methods of deactivation of chemical warfare agents that are necessary on the battlefield, as well as in laboratories, research institutions, and facilities of production, storage, and destruction of poisonous substances. The review presents the main directions of neutralizing warfare poisonous substances, which are the most effective in the conditions of their real use. In the second part of this work, the methods of deactivating warfare poisons using nucleophilic reagents, primarily α-nucleophiles, which have high efficiency and can react as nucleophiles and as oxidants, are considered in detail. A promising area of degradation of such products is the use of supernucleophilic systems based on functionalized detergents, as well as adsorption and photocatalytic deactivation methods. The material presented above shows the importance of general knowledge about the physical and chemical properties of chemical warfare agents, the rate of their decomposition, the advantages and disadvantages of certain available technologies for their application. This review can be useful for finding new and improving known methods for decontamination of chemical warfare agents and other ecotoxicants, and protecting the environment.https://ophcj.nuph.edu.ua/article/view/313307chemical warfare agentsnerve agentsvesicantsdecontaminationdetectionprotection |
| spellingShingle | Olexander E. Shumeiko Mykola I. Korotkikh Chemical Warfare Agents: Structure, Properties, Decontamination (Part 2) Журнал органічної та фармацевтичної хімії chemical warfare agents nerve agents vesicants decontamination detection protection |
| title | Chemical Warfare Agents: Structure, Properties, Decontamination (Part 2) |
| title_full | Chemical Warfare Agents: Structure, Properties, Decontamination (Part 2) |
| title_fullStr | Chemical Warfare Agents: Structure, Properties, Decontamination (Part 2) |
| title_full_unstemmed | Chemical Warfare Agents: Structure, Properties, Decontamination (Part 2) |
| title_short | Chemical Warfare Agents: Structure, Properties, Decontamination (Part 2) |
| title_sort | chemical warfare agents structure properties decontamination part 2 |
| topic | chemical warfare agents nerve agents vesicants decontamination detection protection |
| url | https://ophcj.nuph.edu.ua/article/view/313307 |
| work_keys_str_mv | AT olexandereshumeiko chemicalwarfareagentsstructurepropertiesdecontaminationpart2 AT mykolaikorotkikh chemicalwarfareagentsstructurepropertiesdecontaminationpart2 |