Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.

Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.

Recent genome-wide (GW) scans have identified several independent loci affecting human stature, but their contribution through the different skeletal components of height is still poorly understood. We carried out a genome-wide scan in 12,611 participants, followed by replication in an additional 7,...

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Main Authors: Nicole Soranzo, Fernando Rivadeneira, Usha Chinappen-Horsley, Ida Malkina, J Brent Richards, Naomi Hammond, Lisette Stolk, Alexandra Nica, Michael Inouye, Albert Hofman, Jonathan Stephens, Eleanor Wheeler, Pascal Arp, Rhian Gwilliam, P Mila Jhamai, Simon Potter, Amy Chaney, Mohammed J R Ghori, Radhi Ravindrarajah, Sergey Ermakov, Karol Estrada, Huibert A P Pols, Frances M Williams, Wendy L McArdle, Joyce B van Meurs, Ruth J F Loos, Emmanouil T Dermitzakis, Kourosh R Ahmadi, Deborah J Hart, Willem H Ouwehand, Nicholas J Wareham, Inês Barroso, Manjinder S Sandhu, David P Strachan, Gregory Livshits, Timothy D Spector, André G Uitterlinden, Panos Deloukas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-04-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000445&type=printable
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