Unusual Case of Malignant Struma Ovarii and Cervical Thyroid Cancer Preceded by Ovarian Teratoma: Case Report and Review of the Literature
Objective. To present a rare case of malignant struma ovarii (MSO) and synchronous thyroid cancer, review the medical literature, and present the latest trends in management. Methods. The case of a woman with MSO and concomitant thyroid cancer is presented, including clinical presentation, treatment...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
|
| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2019/7964126 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832558909350477824 |
|---|---|
| author | Elias G. Tzelepis Elena Barengolts Steven Garzon Joseph Shulan Yuval Eisenberg |
| author_facet | Elias G. Tzelepis Elena Barengolts Steven Garzon Joseph Shulan Yuval Eisenberg |
| author_sort | Elias G. Tzelepis |
| collection | DOAJ |
| description | Objective. To present a rare case of malignant struma ovarii (MSO) and synchronous thyroid cancer, review the medical literature, and present the latest trends in management. Methods. The case of a woman with MSO and concomitant thyroid cancer is presented, including clinical presentation, treatment, and follow-up care. A search of the English-language literature was conducted using MEDLINE and Google Scholar data bases. Results. We found 10 publications (one abstract) describing 10 patients with MSO and concomitant thyroid cancer. Six additional patients were reported by a study that analyzed the SEER (cancer registry) database. The median age of women was 42 years, with the majority of them presenting with abdominal symptoms. Histologically, most tumors were papillary carcinomas in both organs. In 5 patients, there was extrathyroidal tumor extension at time of surgery. Conclusion. MSO can occasionally coexist with highly aggressive eutopic thyroid cancer. Although this concurrence is even rarer than MSO, clinicians should routinely investigate for possible synchronous thyroid cancer in all cases of MSO and also consider aggressive postoperative treatment including thyroidectomy and radioiodine ablation therapy in cases of MSO. |
| format | Article |
| id | doaj-art-0983fe725ed945bb9beff193f3a410ce |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-0983fe725ed945bb9beff193f3a410ce2025-02-03T01:31:16ZengWileyCase Reports in Endocrinology2090-65012090-651X2019-01-01201910.1155/2019/79641267964126Unusual Case of Malignant Struma Ovarii and Cervical Thyroid Cancer Preceded by Ovarian Teratoma: Case Report and Review of the LiteratureElias G. Tzelepis0Elena Barengolts1Steven Garzon2Joseph Shulan3Yuval Eisenberg4Division of Endocrinology, Diabetes & Metabolism, University of Illinois at Chicago, Chicago, IL, USADivision of Endocrinology, Diabetes & Metabolism, University of Illinois at Chicago, Chicago, IL, USADepartment of Pathology, University of Illinois at Chicago, Chicago, IL, USADivision of Endocrinology, Diabetes & Metabolism, University of Illinois at Chicago, Chicago, IL, USADivision of Endocrinology, Diabetes & Metabolism, University of Illinois at Chicago, Chicago, IL, USAObjective. To present a rare case of malignant struma ovarii (MSO) and synchronous thyroid cancer, review the medical literature, and present the latest trends in management. Methods. The case of a woman with MSO and concomitant thyroid cancer is presented, including clinical presentation, treatment, and follow-up care. A search of the English-language literature was conducted using MEDLINE and Google Scholar data bases. Results. We found 10 publications (one abstract) describing 10 patients with MSO and concomitant thyroid cancer. Six additional patients were reported by a study that analyzed the SEER (cancer registry) database. The median age of women was 42 years, with the majority of them presenting with abdominal symptoms. Histologically, most tumors were papillary carcinomas in both organs. In 5 patients, there was extrathyroidal tumor extension at time of surgery. Conclusion. MSO can occasionally coexist with highly aggressive eutopic thyroid cancer. Although this concurrence is even rarer than MSO, clinicians should routinely investigate for possible synchronous thyroid cancer in all cases of MSO and also consider aggressive postoperative treatment including thyroidectomy and radioiodine ablation therapy in cases of MSO.http://dx.doi.org/10.1155/2019/7964126 |
| spellingShingle | Elias G. Tzelepis Elena Barengolts Steven Garzon Joseph Shulan Yuval Eisenberg Unusual Case of Malignant Struma Ovarii and Cervical Thyroid Cancer Preceded by Ovarian Teratoma: Case Report and Review of the Literature Case Reports in Endocrinology |
| title | Unusual Case of Malignant Struma Ovarii and Cervical Thyroid Cancer Preceded by Ovarian Teratoma: Case Report and Review of the Literature |
| title_full | Unusual Case of Malignant Struma Ovarii and Cervical Thyroid Cancer Preceded by Ovarian Teratoma: Case Report and Review of the Literature |
| title_fullStr | Unusual Case of Malignant Struma Ovarii and Cervical Thyroid Cancer Preceded by Ovarian Teratoma: Case Report and Review of the Literature |
| title_full_unstemmed | Unusual Case of Malignant Struma Ovarii and Cervical Thyroid Cancer Preceded by Ovarian Teratoma: Case Report and Review of the Literature |
| title_short | Unusual Case of Malignant Struma Ovarii and Cervical Thyroid Cancer Preceded by Ovarian Teratoma: Case Report and Review of the Literature |
| title_sort | unusual case of malignant struma ovarii and cervical thyroid cancer preceded by ovarian teratoma case report and review of the literature |
| url | http://dx.doi.org/10.1155/2019/7964126 |
| work_keys_str_mv | AT eliasgtzelepis unusualcaseofmalignantstrumaovariiandcervicalthyroidcancerprecededbyovarianteratomacasereportandreviewoftheliterature AT elenabarengolts unusualcaseofmalignantstrumaovariiandcervicalthyroidcancerprecededbyovarianteratomacasereportandreviewoftheliterature AT stevengarzon unusualcaseofmalignantstrumaovariiandcervicalthyroidcancerprecededbyovarianteratomacasereportandreviewoftheliterature AT josephshulan unusualcaseofmalignantstrumaovariiandcervicalthyroidcancerprecededbyovarianteratomacasereportandreviewoftheliterature AT yuvaleisenberg unusualcaseofmalignantstrumaovariiandcervicalthyroidcancerprecededbyovarianteratomacasereportandreviewoftheliterature |