Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn?
Purpose. To find out if the serum IgG level in the newborn baby was affected by low maternal serum IgG during pregnancy in two newly diagnosed primary antibody deficient patients. Method. Infant cord blood IgG level was compared with maternal IgG level in 2 mothers with newly diagnosed primary antib...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Immunology |
| Online Access: | http://dx.doi.org/10.1155/2015/286380 |
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| _version_ | 1849305257238069248 |
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| author | Vasantha Nagendran Noel Emmanuel Amolak S. Bansal |
| author_facet | Vasantha Nagendran Noel Emmanuel Amolak S. Bansal |
| author_sort | Vasantha Nagendran |
| collection | DOAJ |
| description | Purpose. To find out if the serum IgG level in the newborn baby was affected by low maternal serum IgG during pregnancy in two newly diagnosed primary antibody deficient patients. Method. Infant cord blood IgG level was compared with maternal IgG level in 2 mothers with newly diagnosed primary antibody deficiency, who declined replacement IgG treatment during pregnancy. Results. Both mothers delivered healthy babies with normal IgG levels at birth. Conclusions. The normal IgG levels and sound health in these 2 babies in spite of low maternal IgG throughout pregnancy raise interesting discussion points about maternofoetal immunoglobulin transport mechanisms in primary antibody deficiency. |
| format | Article |
| id | doaj-art-0982d400b503464cb25d6994ce5b935c |
| institution | Kabale University |
| issn | 2090-6609 2090-6617 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Immunology |
| spelling | doaj-art-0982d400b503464cb25d6994ce5b935c2025-08-20T03:55:31ZengWileyCase Reports in Immunology2090-66092090-66172015-01-01201510.1155/2015/286380286380Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn?Vasantha Nagendran0Noel Emmanuel1Amolak S. Bansal2Epsom and St Helier University Hospitals NHS Trust, Carshalton, Surrey SM5 1AA, UKSt George’s University Hospitals NHS Foundation Trust, Tooting, London SW17 0QT, UKEpsom and St Helier University Hospitals NHS Trust, Carshalton, Surrey SM5 1AA, UKPurpose. To find out if the serum IgG level in the newborn baby was affected by low maternal serum IgG during pregnancy in two newly diagnosed primary antibody deficient patients. Method. Infant cord blood IgG level was compared with maternal IgG level in 2 mothers with newly diagnosed primary antibody deficiency, who declined replacement IgG treatment during pregnancy. Results. Both mothers delivered healthy babies with normal IgG levels at birth. Conclusions. The normal IgG levels and sound health in these 2 babies in spite of low maternal IgG throughout pregnancy raise interesting discussion points about maternofoetal immunoglobulin transport mechanisms in primary antibody deficiency.http://dx.doi.org/10.1155/2015/286380 |
| spellingShingle | Vasantha Nagendran Noel Emmanuel Amolak S. Bansal Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn? Case Reports in Immunology |
| title | Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn? |
| title_full | Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn? |
| title_fullStr | Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn? |
| title_full_unstemmed | Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn? |
| title_short | Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn? |
| title_sort | does the maternal serum igg level during pregnancy in primary antibody deficiency influence the igg level in the newborn |
| url | http://dx.doi.org/10.1155/2015/286380 |
| work_keys_str_mv | AT vasanthanagendran doesthematernalserumigglevelduringpregnancyinprimaryantibodydeficiencyinfluencetheigglevelinthenewborn AT noelemmanuel doesthematernalserumigglevelduringpregnancyinprimaryantibodydeficiencyinfluencetheigglevelinthenewborn AT amolaksbansal doesthematernalserumigglevelduringpregnancyinprimaryantibodydeficiencyinfluencetheigglevelinthenewborn |