EpiGePT: a pretrained transformer-based language model for context-specific human epigenomics
Abstract The inherent similarities between natural language and biological sequences have inspired the use of large language models in genomics, but current models struggle to incorporate chromatin interactions or predict in unseen cellular contexts. To address this, we propose EpiGePT, a transforme...
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| Main Authors: | Zijing Gao, Qiao Liu, Wanwen Zeng, Rui Jiang, Wing Hung Wong |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
|
| Series: | Genome Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13059-024-03449-7 |
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