Effects of botulinum toxin type A on healing of injured skeletal muscles

<b>Objectives:</b> (1) Evaluation of microscopic healing of skeletal muscle fibers after injuries, especially the arrangement of new muscle fibers and scar tissue diameter in the injury region. (2) Evaluation of alterations in microscopy of the healing procedure within skeletal muscles...

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Main Authors: Shokravi Ramin, Moshref Mohammad, Eslami Behnam, Aghmasheh Farhad
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2007-01-01
Series:Indian Journal of Plastic Surgery
Subjects:
Online Access:http://www.ijps.org/article.asp?issn=0970-0358;year=2007;volume=40;issue=2;spage=129;epage=132;aulast=Shokravi
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author Shokravi Ramin
Moshref Mohammad
Eslami Behnam
Aghmasheh Farhad
author_facet Shokravi Ramin
Moshref Mohammad
Eslami Behnam
Aghmasheh Farhad
author_sort Shokravi Ramin
collection DOAJ
description <b>Objectives:</b> (1) Evaluation of microscopic healing of skeletal muscle fibers after injuries, especially the arrangement of new muscle fibers and scar tissue diameter in the injury region. (2) Evaluation of alterations in microscopy of the healing procedure within skeletal muscles after injury following botulinum toxin type A (BTX -A) induced muscle immobilization. <b> Materials and Methods:</b> The study was done on 12 white lab rabbits of either sex in a 6-month period. <b> Results:</b> The immobilization of skeletal muscle fibers as a result of the use of BTX-A after injury caused a qualitative increase in fibrous tissue formation in the area of injury, and the BTX-A-induced immobilization for a period of 6 months led to muscle atrophy.
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issn 0970-0358
language English
publishDate 2007-01-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Indian Journal of Plastic Surgery
spelling doaj-art-095fbf6f3e404632a0953e9f0901ec902025-08-20T01:58:48ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Plastic Surgery0970-03582007-01-01402129132Effects of botulinum toxin type A on healing of injured skeletal musclesShokravi RaminMoshref MohammadEslami BehnamAghmasheh Farhad<b>Objectives:</b> (1) Evaluation of microscopic healing of skeletal muscle fibers after injuries, especially the arrangement of new muscle fibers and scar tissue diameter in the injury region. (2) Evaluation of alterations in microscopy of the healing procedure within skeletal muscles after injury following botulinum toxin type A (BTX -A) induced muscle immobilization. <b> Materials and Methods:</b> The study was done on 12 white lab rabbits of either sex in a 6-month period. <b> Results:</b> The immobilization of skeletal muscle fibers as a result of the use of BTX-A after injury caused a qualitative increase in fibrous tissue formation in the area of injury, and the BTX-A-induced immobilization for a period of 6 months led to muscle atrophy.http://www.ijps.org/article.asp?issn=0970-0358;year=2007;volume=40;issue=2;spage=129;epage=132;aulast=ShokraviBotulinum toxinskeletal muscleswound healing
spellingShingle Shokravi Ramin
Moshref Mohammad
Eslami Behnam
Aghmasheh Farhad
Effects of botulinum toxin type A on healing of injured skeletal muscles
Indian Journal of Plastic Surgery
Botulinum toxin
skeletal muscles
wound healing
title Effects of botulinum toxin type A on healing of injured skeletal muscles
title_full Effects of botulinum toxin type A on healing of injured skeletal muscles
title_fullStr Effects of botulinum toxin type A on healing of injured skeletal muscles
title_full_unstemmed Effects of botulinum toxin type A on healing of injured skeletal muscles
title_short Effects of botulinum toxin type A on healing of injured skeletal muscles
title_sort effects of botulinum toxin type a on healing of injured skeletal muscles
topic Botulinum toxin
skeletal muscles
wound healing
url http://www.ijps.org/article.asp?issn=0970-0358;year=2007;volume=40;issue=2;spage=129;epage=132;aulast=Shokravi
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AT moshrefmohammad effectsofbotulinumtoxintypeaonhealingofinjuredskeletalmuscles
AT eslamibehnam effectsofbotulinumtoxintypeaonhealingofinjuredskeletalmuscles
AT aghmashehfarhad effectsofbotulinumtoxintypeaonhealingofinjuredskeletalmuscles