Oral health status in children with familial Mediterranean fever

Background. Familial Mediterranean fever (FMF) is the most common hereditary autoinflammatory disease. We aimed to investigate the oral health status and oral hygiene habits in children with FMF. Methods. In this cross-sectional study, 199 children with FMF, aged between 3-18 years, we...

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Main Authors: Pelin Esmeray, Tülin İleri Keçeli, Meryem Tekçiçek, Ezgi Deniz Batu, Zehra Serap Arıcı, Hande Konşuk Ünlü, Seza Özen, Yelda Bilginer
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Language:English
Published: Hacettepe University Institute of Child Health 2021-06-01
Series:The Turkish Journal of Pediatrics
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Online Access:https://turkjpediatr.org/article/view/318
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author Pelin Esmeray
Tülin İleri Keçeli
Meryem Tekçiçek
Ezgi Deniz Batu
Zehra Serap Arıcı
Hande Konşuk Ünlü
Seza Özen
Yelda Bilginer
author_facet Pelin Esmeray
Tülin İleri Keçeli
Meryem Tekçiçek
Ezgi Deniz Batu
Zehra Serap Arıcı
Hande Konşuk Ünlü
Seza Özen
Yelda Bilginer
author_sort Pelin Esmeray
collection DOAJ
description Background. Familial Mediterranean fever (FMF) is the most common hereditary autoinflammatory disease. We aimed to investigate the oral health status and oral hygiene habits in children with FMF. Methods. In this cross-sectional study, 199 children with FMF, aged between 3-18 years, were included. Demographic findings and oral hygiene habits of children were questioned by face-to-face interview. Oral health status of patients was evaluated using decay-missing-filled index [DMFT (decay-missing-filled teeth), DMFS (decay-missing-filled teeth) for permanent; dmft, dmfs for primary teeth], the International Caries Detection and Assessment System (ICDAS-II) index, PUFA / pufa index [the presence of severely decayed teeth with visible pulpal involvement (P/p), ulceration caused by dislocated tooth fragments (U/u), fistula (F/f) and abscess (A/a)], gingival (GI) and plaque index (PI). In addition to these, occlusion, oral soft and hard tissues were examined. Results. One-hundred-nine (54.8%) of children had at least one decayed permanent tooth and 81.2% of children had at least one decayed primary tooth. The mean DMFT was 1.91±2.45, DMFS was 3.1±4.49, dmft was 3.95±3.54, dmfs was 8.62±8.88, PI was 1.17±0.44, GI was 0.85±0.39. Aphthous mouth ulcer occurred in 19 (9.5%) patients. Recurrent aphthous mouth ulcers were more frequent among patients with one exon-ten and one exon-two mutations than patients with one exon-10 mutation, two exon-ten mutations, or two exon-2 mutations (61.1% vs. 47.9%, 26.1%, 20%, respectively p < 0.001). Tooth decay was more frequent among patients who had attacks in the last six months than those who did not have any attacks during the last six months (97.4% vs. 87.7%, p=0.017). Conclusion. Dental caries and periodontal disease, which are public health problems, were seen at a high percentage of children with FMF in our study.
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publishDate 2021-06-01
publisher Hacettepe University Institute of Child Health
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spelling doaj-art-095f0c358baf42ba8295c444d372292b2025-08-20T03:16:22ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212021-06-0163310.24953/turkjped.2021.03.011Oral health status in children with familial Mediterranean feverPelin Esmeray0Tülin İleri Keçeli1Meryem Tekçiçek2Ezgi Deniz Batu3Zehra Serap Arıcı4Hande Konşuk Ünlü5Seza Özen6Yelda Bilginer7Department of Pediatrics, Erzurum Training and Research Hospital, Erzurum, Turkey.Department of Pediatric Dentistry, Hacettepe University Faculty of Dentistry, Ankara, Turkey.Department of Pediatric Dentistry, Hacettepe University Faculty of Dentistry, Ankara, Turkey.Department of Pediatrics, Division of Pediatric Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey.Şanlıurfa Training and Research Hospital, Department of Pediatric Rheumatology, Şanlıurfa, Turkey.Hacettepe University Institute of Public Health, Ankara, Turkey.Department of Pediatrics, Division of Pediatric Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey.Department of Pediatrics, Division of Pediatric Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey. Background. Familial Mediterranean fever (FMF) is the most common hereditary autoinflammatory disease. We aimed to investigate the oral health status and oral hygiene habits in children with FMF. Methods. In this cross-sectional study, 199 children with FMF, aged between 3-18 years, were included. Demographic findings and oral hygiene habits of children were questioned by face-to-face interview. Oral health status of patients was evaluated using decay-missing-filled index [DMFT (decay-missing-filled teeth), DMFS (decay-missing-filled teeth) for permanent; dmft, dmfs for primary teeth], the International Caries Detection and Assessment System (ICDAS-II) index, PUFA / pufa index [the presence of severely decayed teeth with visible pulpal involvement (P/p), ulceration caused by dislocated tooth fragments (U/u), fistula (F/f) and abscess (A/a)], gingival (GI) and plaque index (PI). In addition to these, occlusion, oral soft and hard tissues were examined. Results. One-hundred-nine (54.8%) of children had at least one decayed permanent tooth and 81.2% of children had at least one decayed primary tooth. The mean DMFT was 1.91±2.45, DMFS was 3.1±4.49, dmft was 3.95±3.54, dmfs was 8.62±8.88, PI was 1.17±0.44, GI was 0.85±0.39. Aphthous mouth ulcer occurred in 19 (9.5%) patients. Recurrent aphthous mouth ulcers were more frequent among patients with one exon-ten and one exon-two mutations than patients with one exon-10 mutation, two exon-ten mutations, or two exon-2 mutations (61.1% vs. 47.9%, 26.1%, 20%, respectively p < 0.001). Tooth decay was more frequent among patients who had attacks in the last six months than those who did not have any attacks during the last six months (97.4% vs. 87.7%, p=0.017). Conclusion. Dental caries and periodontal disease, which are public health problems, were seen at a high percentage of children with FMF in our study. https://turkjpediatr.org/article/view/318dental cariesfamilial Mediterranean feveroral hygieneperiodontal disease
spellingShingle Pelin Esmeray
Tülin İleri Keçeli
Meryem Tekçiçek
Ezgi Deniz Batu
Zehra Serap Arıcı
Hande Konşuk Ünlü
Seza Özen
Yelda Bilginer
Oral health status in children with familial Mediterranean fever
The Turkish Journal of Pediatrics
dental caries
familial Mediterranean fever
oral hygiene
periodontal disease
title Oral health status in children with familial Mediterranean fever
title_full Oral health status in children with familial Mediterranean fever
title_fullStr Oral health status in children with familial Mediterranean fever
title_full_unstemmed Oral health status in children with familial Mediterranean fever
title_short Oral health status in children with familial Mediterranean fever
title_sort oral health status in children with familial mediterranean fever
topic dental caries
familial Mediterranean fever
oral hygiene
periodontal disease
url https://turkjpediatr.org/article/view/318
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AT tulinilerikeceli oralhealthstatusinchildrenwithfamilialmediterraneanfever
AT meryemtekcicek oralhealthstatusinchildrenwithfamilialmediterraneanfever
AT ezgidenizbatu oralhealthstatusinchildrenwithfamilialmediterraneanfever
AT zehraseraparıcı oralhealthstatusinchildrenwithfamilialmediterraneanfever
AT handekonsukunlu oralhealthstatusinchildrenwithfamilialmediterraneanfever
AT sezaozen oralhealthstatusinchildrenwithfamilialmediterraneanfever
AT yeldabilginer oralhealthstatusinchildrenwithfamilialmediterraneanfever