Cryopreservation of Parathyroid Glands

The risk of permanent hypoparathyroidism following thyroid and parathyroid surgery is around 1% in the hands of experienced endocrine surgeons. Although this complication is rare, rendering a patient permanently aparathyroid has significant consequences on the health and quality of life of the pati...

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Main Author: Marlon A. Guerrero
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2010/829540
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author Marlon A. Guerrero
author_facet Marlon A. Guerrero
author_sort Marlon A. Guerrero
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description The risk of permanent hypoparathyroidism following thyroid and parathyroid surgery is around 1% in the hands of experienced endocrine surgeons. Although this complication is rare, rendering a patient permanently aparathyroid has significant consequences on the health and quality of life of the patient. Immediate autotransplantation of parathyroid glands that are injured or unintentionally removed offers the best possibility of graft viability and functionality. However, since the majority of cases of hypoparathyroidism are transient, immediate autotransplantation can complicate postoperative surveillance in certain patients, especially those with primary hyperparathyroidism. Cryopreservation of parathyroid tissue is an alternate technique that was developed to treat patients with permanent hypoparathyroidism. This method allows for parathyroid tissue to be stored and then autotransplanted in a delayed fashion once permanent hypoparathyroidism is confirmed. This article provides a contemporary review on cryopreservation of parathyroid tissue and its current role in thyroid and parathyroid surgery.
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spelling doaj-art-095a3f2cc3a447d39a628bb3bb8882f82025-08-20T03:55:29ZengWileyInternational Journal of Endocrinology1687-83371687-83452010-01-01201010.1155/2010/829540829540Cryopreservation of Parathyroid GlandsMarlon A. Guerrero0Department of Surgery, The University of Arizona, 1501 N. Campbell Avenue, Tucson, AZ 85724, USAThe risk of permanent hypoparathyroidism following thyroid and parathyroid surgery is around 1% in the hands of experienced endocrine surgeons. Although this complication is rare, rendering a patient permanently aparathyroid has significant consequences on the health and quality of life of the patient. Immediate autotransplantation of parathyroid glands that are injured or unintentionally removed offers the best possibility of graft viability and functionality. However, since the majority of cases of hypoparathyroidism are transient, immediate autotransplantation can complicate postoperative surveillance in certain patients, especially those with primary hyperparathyroidism. Cryopreservation of parathyroid tissue is an alternate technique that was developed to treat patients with permanent hypoparathyroidism. This method allows for parathyroid tissue to be stored and then autotransplanted in a delayed fashion once permanent hypoparathyroidism is confirmed. This article provides a contemporary review on cryopreservation of parathyroid tissue and its current role in thyroid and parathyroid surgery.http://dx.doi.org/10.1155/2010/829540
spellingShingle Marlon A. Guerrero
Cryopreservation of Parathyroid Glands
International Journal of Endocrinology
title Cryopreservation of Parathyroid Glands
title_full Cryopreservation of Parathyroid Glands
title_fullStr Cryopreservation of Parathyroid Glands
title_full_unstemmed Cryopreservation of Parathyroid Glands
title_short Cryopreservation of Parathyroid Glands
title_sort cryopreservation of parathyroid glands
url http://dx.doi.org/10.1155/2010/829540
work_keys_str_mv AT marlonaguerrero cryopreservationofparathyroidglands