Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in Turkey

OBJECTIVE: In this study, we aimed to determine the frequency of etiologic factors that causes postmenopausal bleeding. STUDY DESIGN: For the purpose, a total number of 200 women with postmenopausal bleeding were included in the study. Medical records regarding history, physical examination, and e...

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Main Authors: Umit Yasemin Sert, Ismail Guler, Tuncay Nas
Format: Article
Language:English
Published: Medical Network 2021-04-01
Series:Gynecology Obstetrics & Reproductive Medicine
Subjects:
Online Access:https://gorm.com.tr/index.php/GORM/article/view/1007
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author Umit Yasemin Sert
Ismail Guler
Tuncay Nas
author_facet Umit Yasemin Sert
Ismail Guler
Tuncay Nas
author_sort Umit Yasemin Sert
collection DOAJ
description OBJECTIVE: In this study, we aimed to determine the frequency of etiologic factors that causes postmenopausal bleeding. STUDY DESIGN: For the purpose, a total number of 200 women with postmenopausal bleeding were included in the study. Medical records regarding history, physical examination, and endometrium biopsy of these cases were retrospectively analyzed. The frequency of etiologic factors and relevancy of pathological results with demographic factors were determined. RESULTS: Most frequent histopathologic diagnosis of the women with postmenopausal bleeding were established as endometrial atrophy, endometrial polyp, inadequate material, cancer, proliferative endometrium, endometrial hyperplasia, and other disorders respectively. Contrarily the previous studies, our study showed that estrogen replacement therapy was not a reason for postmenopausal bleeding. CONCLUSION: Although endometrial atrophy is the most frequent cause, postmenopausal bleeding should promptly be evaluated since endometrial hyperplasia and cancer are frequently the underlying cause. We found that premalignant and malignant lesions were related to the patients’ BMI (body mass index), duration of postmenopause, the presence of diabetes, determination of thick endometrium by ultrasonography.
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series Gynecology Obstetrics & Reproductive Medicine
spelling doaj-art-09562537ebe44123aaf5f493112befba2025-02-11T21:11:48ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182021-04-0127110.21613/GORM.2019.1007Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in TurkeyUmit Yasemin SertIsmail Guler0Tuncay Nas1Gazi University Department of Obstetrics and GynecologyGazi University Department of Obstetrics and Gynecology OBJECTIVE: In this study, we aimed to determine the frequency of etiologic factors that causes postmenopausal bleeding. STUDY DESIGN: For the purpose, a total number of 200 women with postmenopausal bleeding were included in the study. Medical records regarding history, physical examination, and endometrium biopsy of these cases were retrospectively analyzed. The frequency of etiologic factors and relevancy of pathological results with demographic factors were determined. RESULTS: Most frequent histopathologic diagnosis of the women with postmenopausal bleeding were established as endometrial atrophy, endometrial polyp, inadequate material, cancer, proliferative endometrium, endometrial hyperplasia, and other disorders respectively. Contrarily the previous studies, our study showed that estrogen replacement therapy was not a reason for postmenopausal bleeding. CONCLUSION: Although endometrial atrophy is the most frequent cause, postmenopausal bleeding should promptly be evaluated since endometrial hyperplasia and cancer are frequently the underlying cause. We found that premalignant and malignant lesions were related to the patients’ BMI (body mass index), duration of postmenopause, the presence of diabetes, determination of thick endometrium by ultrasonography. https://gorm.com.tr/index.php/GORM/article/view/1007AtrophyEstrogen replacement therapyPostmenopausal bleeding
spellingShingle Umit Yasemin Sert
Ismail Guler
Tuncay Nas
Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in Turkey
Gynecology Obstetrics & Reproductive Medicine
Atrophy
Estrogen replacement therapy
Postmenopausal bleeding
title Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in Turkey
title_full Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in Turkey
title_fullStr Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in Turkey
title_full_unstemmed Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in Turkey
title_short Frequency of the Causes of Postmenopausal Bleeding, Results of a Tertiary Referral Center in Turkey
title_sort frequency of the causes of postmenopausal bleeding results of a tertiary referral center in turkey
topic Atrophy
Estrogen replacement therapy
Postmenopausal bleeding
url https://gorm.com.tr/index.php/GORM/article/view/1007
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