Optimizing spatial distribution of wastewater-based epidemiology to advance health equity

In 2022, the US Centers for Disease Control and Prevention commissioned the National Academies of Sciences, Engineering, and Medicine to assess the role of community-level wastewater-based epidemiology (WBE) beyond COVID-19. WBE is recognized as a promising mechanism for promptly identifying infecti...

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Main Authors: Maria L. Daza-Torres, J. Cricelio Montesinos-López, César Herrera, Yury E. García, Colleen C. Naughton, Heather N. Bischel, Miriam Nuño
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Epidemics
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Online Access:http://www.sciencedirect.com/science/article/pii/S1755436524000653
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author Maria L. Daza-Torres
J. Cricelio Montesinos-López
César Herrera
Yury E. García
Colleen C. Naughton
Heather N. Bischel
Miriam Nuño
author_facet Maria L. Daza-Torres
J. Cricelio Montesinos-López
César Herrera
Yury E. García
Colleen C. Naughton
Heather N. Bischel
Miriam Nuño
author_sort Maria L. Daza-Torres
collection DOAJ
description In 2022, the US Centers for Disease Control and Prevention commissioned the National Academies of Sciences, Engineering, and Medicine to assess the role of community-level wastewater-based epidemiology (WBE) beyond COVID-19. WBE is recognized as a promising mechanism for promptly identifying infectious diseases, including COVID-19 and other novel pathogens. An important conclusion from this initiative is the critical importance of maintaining equity and expanding access to fully realize the benefits of wastewater surveillance for marginalized communities. To address this need, we propose an optimization framework that strategically allocates wastewater monitoring resources at the wastewater treatment plant (WWTP) level, ensuring more effective and equitable distribution of surveillance efforts to serve underserved populations.The purpose of the framework is to obtain a balanced spatial distribution, inclusive population coverage, and efficient representation of disadvantaged groups in the allocation of resources for WBE. Furthermore, the framework concentrates on areas with high population density and gives priority to vulnerable regions, as well as identifying signals that display significant variations from other monitored sources. The optimization objective is to maximize a weighted combination of these critical factors. This problem is formulated as an integer optimization problem and solved using simulated annealing. We evaluate various scenarios, considering different weighting factors, to optimize the allocation of WWTPs with monitoring systems. This optimization framework provides an opportunity to enhance WBE by providing customized monitoring strategies created to address specific priorities and situations, thus enhancing the decision-making processes in public health responses.
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spelling doaj-art-09437ec69bcc4a1b8ef4cd69156b9ef22025-08-20T01:56:45ZengElsevierEpidemics1755-43652024-12-014910080410.1016/j.epidem.2024.100804Optimizing spatial distribution of wastewater-based epidemiology to advance health equityMaria L. Daza-Torres0J. Cricelio Montesinos-López1César Herrera2Yury E. García3Colleen C. Naughton4Heather N. Bischel5Miriam Nuño6Department of Public Health Sciences, University of California Davis, CA 95616, United StatesDepartment of Public Health Sciences, University of California Davis, CA 95616, United StatesDepartment of Mathematics, Purdue University, IN 47907, United StatesDepartment of Public Health Sciences, University of California Davis, CA 95616, United StatesDepartment of Civil and Environmental Engineering, University of California Merced, Merced, CA, USADepartment of Civil and Environmental Engineering, University of California Davis, Davis, CA, USADepartment of Public Health Sciences, University of California Davis, CA 95616, United States; Corresponding author.In 2022, the US Centers for Disease Control and Prevention commissioned the National Academies of Sciences, Engineering, and Medicine to assess the role of community-level wastewater-based epidemiology (WBE) beyond COVID-19. WBE is recognized as a promising mechanism for promptly identifying infectious diseases, including COVID-19 and other novel pathogens. An important conclusion from this initiative is the critical importance of maintaining equity and expanding access to fully realize the benefits of wastewater surveillance for marginalized communities. To address this need, we propose an optimization framework that strategically allocates wastewater monitoring resources at the wastewater treatment plant (WWTP) level, ensuring more effective and equitable distribution of surveillance efforts to serve underserved populations.The purpose of the framework is to obtain a balanced spatial distribution, inclusive population coverage, and efficient representation of disadvantaged groups in the allocation of resources for WBE. Furthermore, the framework concentrates on areas with high population density and gives priority to vulnerable regions, as well as identifying signals that display significant variations from other monitored sources. The optimization objective is to maximize a weighted combination of these critical factors. This problem is formulated as an integer optimization problem and solved using simulated annealing. We evaluate various scenarios, considering different weighting factors, to optimize the allocation of WWTPs with monitoring systems. This optimization framework provides an opportunity to enhance WBE by providing customized monitoring strategies created to address specific priorities and situations, thus enhancing the decision-making processes in public health responses.http://www.sciencedirect.com/science/article/pii/S1755436524000653Wastewater-based epidemiologyCOVID-19SARS-CoV-2Infectious diseasePublic health
spellingShingle Maria L. Daza-Torres
J. Cricelio Montesinos-López
César Herrera
Yury E. García
Colleen C. Naughton
Heather N. Bischel
Miriam Nuño
Optimizing spatial distribution of wastewater-based epidemiology to advance health equity
Epidemics
Wastewater-based epidemiology
COVID-19
SARS-CoV-2
Infectious disease
Public health
title Optimizing spatial distribution of wastewater-based epidemiology to advance health equity
title_full Optimizing spatial distribution of wastewater-based epidemiology to advance health equity
title_fullStr Optimizing spatial distribution of wastewater-based epidemiology to advance health equity
title_full_unstemmed Optimizing spatial distribution of wastewater-based epidemiology to advance health equity
title_short Optimizing spatial distribution of wastewater-based epidemiology to advance health equity
title_sort optimizing spatial distribution of wastewater based epidemiology to advance health equity
topic Wastewater-based epidemiology
COVID-19
SARS-CoV-2
Infectious disease
Public health
url http://www.sciencedirect.com/science/article/pii/S1755436524000653
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