Multifocal Extranodal Involvement of Diffuse Large B-Cell Lymphoma
Endobronchial involvement of extrapulmonary malignant tumors is uncommon and mostly associated with breast, kidney, colon, and rectum carcinomas. A 68-year-old male with a prior diagnosis of colon non-Hodgkin lymphoma (NHL) was admitted to the hospital with a complaint of cough, sputum, and dyspnea....
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Pulmonology |
| Online Access: | http://dx.doi.org/10.1155/2013/794642 |
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| author | Devrim Cabuk Y. Taha Gullu Ilknur Basyigit Ozgur Acikgoz Kazım Uygun Kursat Yildiz Fusun Yildiz |
| author_facet | Devrim Cabuk Y. Taha Gullu Ilknur Basyigit Ozgur Acikgoz Kazım Uygun Kursat Yildiz Fusun Yildiz |
| author_sort | Devrim Cabuk |
| collection | DOAJ |
| description | Endobronchial involvement of extrapulmonary malignant tumors is uncommon and mostly associated with breast, kidney, colon, and rectum carcinomas. A 68-year-old male with a prior diagnosis of colon non-Hodgkin lymphoma (NHL) was admitted to the hospital with a complaint of cough, sputum, and dyspnea. The chest radiograph showed right hilar enlargement and opacity at the right middle zone suggestive of a mass lesion. Computed tomography of thorax revealed a right-sided mass lesion extending to thoracic wall with the destruction of the third and the fourth ribs and a right hilar mass lesion. Fiberoptic bronchoscopy was performed in order to evaluate endobronchial involvement and showed stenosis with mucosal tumor infiltration in right upper lobe bronchus. The pathological examination of bronchoscopic biopsy specimen reported diffuse large B-cell lymphoma and the patient was accepted as the endobronchial recurrence of sigmoid colon NHL. The patient is still under treatment of R-ICE (rituximab-ifosfamide-carboplatin-etoposide) chemotherapy and partial regression of pulmonary lesions was noted after 3 courses of treatment. |
| format | Article |
| id | doaj-art-0933b295c6f34799931580bdeb9f75d7 |
| institution | Kabale University |
| issn | 2090-6846 2090-6854 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pulmonology |
| spelling | doaj-art-0933b295c6f34799931580bdeb9f75d72025-02-03T01:04:56ZengWileyCase Reports in Pulmonology2090-68462090-68542013-01-01201310.1155/2013/794642794642Multifocal Extranodal Involvement of Diffuse Large B-Cell LymphomaDevrim Cabuk0Y. Taha Gullu1Ilknur Basyigit2Ozgur Acikgoz3Kazım Uygun4Kursat Yildiz5Fusun Yildiz6Department of Medical Oncology, Kocaeli University Hospital, Umuttepe, 41380 Kocaeli, TurkeyDepartment of Pulmonary Disease, Kocaeli University Hospital, Umuttepe, 41380 Kocaeli, TurkeyDepartment of Pulmonary Disease, Kocaeli University Hospital, Umuttepe, 41380 Kocaeli, TurkeyDepartment of Medical Oncology, Kocaeli University Hospital, Umuttepe, 41380 Kocaeli, TurkeyDepartment of Medical Oncology, Kocaeli University Hospital, Umuttepe, 41380 Kocaeli, TurkeyDepartment of Pathology, Kocaeli University Hospital, Umuttepe, 41380 Kocaeli, TurkeyDepartment of Pulmonary Disease, Kocaeli University Hospital, Umuttepe, 41380 Kocaeli, TurkeyEndobronchial involvement of extrapulmonary malignant tumors is uncommon and mostly associated with breast, kidney, colon, and rectum carcinomas. A 68-year-old male with a prior diagnosis of colon non-Hodgkin lymphoma (NHL) was admitted to the hospital with a complaint of cough, sputum, and dyspnea. The chest radiograph showed right hilar enlargement and opacity at the right middle zone suggestive of a mass lesion. Computed tomography of thorax revealed a right-sided mass lesion extending to thoracic wall with the destruction of the third and the fourth ribs and a right hilar mass lesion. Fiberoptic bronchoscopy was performed in order to evaluate endobronchial involvement and showed stenosis with mucosal tumor infiltration in right upper lobe bronchus. The pathological examination of bronchoscopic biopsy specimen reported diffuse large B-cell lymphoma and the patient was accepted as the endobronchial recurrence of sigmoid colon NHL. The patient is still under treatment of R-ICE (rituximab-ifosfamide-carboplatin-etoposide) chemotherapy and partial regression of pulmonary lesions was noted after 3 courses of treatment.http://dx.doi.org/10.1155/2013/794642 |
| spellingShingle | Devrim Cabuk Y. Taha Gullu Ilknur Basyigit Ozgur Acikgoz Kazım Uygun Kursat Yildiz Fusun Yildiz Multifocal Extranodal Involvement of Diffuse Large B-Cell Lymphoma Case Reports in Pulmonology |
| title | Multifocal Extranodal Involvement of Diffuse Large B-Cell Lymphoma |
| title_full | Multifocal Extranodal Involvement of Diffuse Large B-Cell Lymphoma |
| title_fullStr | Multifocal Extranodal Involvement of Diffuse Large B-Cell Lymphoma |
| title_full_unstemmed | Multifocal Extranodal Involvement of Diffuse Large B-Cell Lymphoma |
| title_short | Multifocal Extranodal Involvement of Diffuse Large B-Cell Lymphoma |
| title_sort | multifocal extranodal involvement of diffuse large b cell lymphoma |
| url | http://dx.doi.org/10.1155/2013/794642 |
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