Comparative analysis of adolescent intramedullary nailing and locking plate fixation for femoral shaft fractures
BackgroundFemoral shaft fractures in adolescents are commonly treated with either antegrade intramedullary nailing (AIN) or lateral plate (LP) fixation. This study compared the clinical outcomes of these two methods.MethodsAdolescent patients with femoral shaft fractures were randomly assigned to ei...
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2025.1614146/full |
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| author | Jian Huang Yiqun Bian |
| author_facet | Jian Huang Yiqun Bian |
| author_sort | Jian Huang |
| collection | DOAJ |
| description | BackgroundFemoral shaft fractures in adolescents are commonly treated with either antegrade intramedullary nailing (AIN) or lateral plate (LP) fixation. This study compared the clinical outcomes of these two methods.MethodsAdolescent patients with femoral shaft fractures were randomly assigned to either the AIN group (n = 62) or the LP group (n = 62). Surgical parameters, early recovery metrics, levels of inflammatory cytokines, pain mediators, and bone metabolism markers were assessed.ResultsThe AIN group had significantly shorter incision lengths (6.8 vs. 8.5 cm, p < 0.001) and lower intraoperative blood loss (120 vs. 170 ml, p < 0.001) compared to the LP group. AIN patients began weight-bearing activities earlier (34 vs. 47 days, p < 0.01). Three months post-operation, the AIN group showed superior proximal femoral geometry and hip function, with a higher non-arthritic hip score (NAHS, 87 vs. 75, p < 0.001). One-week post-operation, the AIN group had lower serum levels of inflammatory cytokines and pain mediators, indicating a reduced inflammatory response and less postoperative pain.ConclusionsAIN offers significant advantages over LP in treating adolescent femoral shaft fractures, including reduced surgical trauma, faster early recovery, lower inflammatory response, less postoperative pain, and enhanced bone healing. |
| format | Article |
| id | doaj-art-09306a48059e4fc79980e211b1d2e1e4 |
| institution | DOAJ |
| issn | 2296-875X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Surgery |
| spelling | doaj-art-09306a48059e4fc79980e211b1d2e1e42025-08-20T02:40:51ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2025-07-011210.3389/fsurg.2025.16141461614146Comparative analysis of adolescent intramedullary nailing and locking plate fixation for femoral shaft fracturesJian HuangYiqun BianBackgroundFemoral shaft fractures in adolescents are commonly treated with either antegrade intramedullary nailing (AIN) or lateral plate (LP) fixation. This study compared the clinical outcomes of these two methods.MethodsAdolescent patients with femoral shaft fractures were randomly assigned to either the AIN group (n = 62) or the LP group (n = 62). Surgical parameters, early recovery metrics, levels of inflammatory cytokines, pain mediators, and bone metabolism markers were assessed.ResultsThe AIN group had significantly shorter incision lengths (6.8 vs. 8.5 cm, p < 0.001) and lower intraoperative blood loss (120 vs. 170 ml, p < 0.001) compared to the LP group. AIN patients began weight-bearing activities earlier (34 vs. 47 days, p < 0.01). Three months post-operation, the AIN group showed superior proximal femoral geometry and hip function, with a higher non-arthritic hip score (NAHS, 87 vs. 75, p < 0.001). One-week post-operation, the AIN group had lower serum levels of inflammatory cytokines and pain mediators, indicating a reduced inflammatory response and less postoperative pain.ConclusionsAIN offers significant advantages over LP in treating adolescent femoral shaft fractures, including reduced surgical trauma, faster early recovery, lower inflammatory response, less postoperative pain, and enhanced bone healing.https://www.frontiersin.org/articles/10.3389/fsurg.2025.1614146/fulladolescent femoral shaft fracturesantegrade intramedullary nailingbone healinginflammationlateral plate fixation |
| spellingShingle | Jian Huang Yiqun Bian Comparative analysis of adolescent intramedullary nailing and locking plate fixation for femoral shaft fractures Frontiers in Surgery adolescent femoral shaft fractures antegrade intramedullary nailing bone healing inflammation lateral plate fixation |
| title | Comparative analysis of adolescent intramedullary nailing and locking plate fixation for femoral shaft fractures |
| title_full | Comparative analysis of adolescent intramedullary nailing and locking plate fixation for femoral shaft fractures |
| title_fullStr | Comparative analysis of adolescent intramedullary nailing and locking plate fixation for femoral shaft fractures |
| title_full_unstemmed | Comparative analysis of adolescent intramedullary nailing and locking plate fixation for femoral shaft fractures |
| title_short | Comparative analysis of adolescent intramedullary nailing and locking plate fixation for femoral shaft fractures |
| title_sort | comparative analysis of adolescent intramedullary nailing and locking plate fixation for femoral shaft fractures |
| topic | adolescent femoral shaft fractures antegrade intramedullary nailing bone healing inflammation lateral plate fixation |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2025.1614146/full |
| work_keys_str_mv | AT jianhuang comparativeanalysisofadolescentintramedullarynailingandlockingplatefixationforfemoralshaftfractures AT yiqunbian comparativeanalysisofadolescentintramedullarynailingandlockingplatefixationforfemoralshaftfractures |