Comparative chloroplast genome analysis of five widespread species (Zanthoxylum L.) and development of molecular markers for their discrimination

BackgroundZanthoxylum L., an important genus in the Rutaceae family, has great edible and medical values. However, the high degree of morphological similarity among Zanthoxylum species and the lack of sufficient chloroplast (cp) genomic resources have greatly impeded germplasm identification and phy...

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Main Authors: Chong Sun, Huamin Liu, Yuan Guo, Xueqian Fu, Xinxin Zhu, Han Liu, Ning Tang, Zexiong Chen, Yiqing Liu, Xia Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Genetics
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Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1495891/full
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author Chong Sun
Chong Sun
Huamin Liu
Yuan Guo
Xueqian Fu
Xinxin Zhu
Han Liu
Han Liu
Ning Tang
Zexiong Chen
Yiqing Liu
Yiqing Liu
Xia Liu
author_facet Chong Sun
Chong Sun
Huamin Liu
Yuan Guo
Xueqian Fu
Xinxin Zhu
Han Liu
Han Liu
Ning Tang
Zexiong Chen
Yiqing Liu
Yiqing Liu
Xia Liu
author_sort Chong Sun
collection DOAJ
description BackgroundZanthoxylum L., an important genus in the Rutaceae family, has great edible and medical values. However, the high degree of morphological similarity among Zanthoxylum species and the lack of sufficient chloroplast (cp) genomic resources have greatly impeded germplasm identification and phylogenetic analyses of Zanthoxylum.MethodsHere we assembled cp genomes of five widespread species (Zanthoxylum bungeanum, Z. armatum, Z. nitidum, Z. ailanthoides and Z. piasezkii) in China as a case study, comparative analysis of these assembled cp genomes.ResultsEach of them, ranging from 157,231 to 158,728 bp, has a quadripartite structure. Except for one extra gene in Z. piasezkii, 132 genes were identified in each species, including 87 encode protein genes, 37 transfer ribose nucleic acid (tRNA) genes, and eight ribosomal RNA (rRNA) genes. Substantial variation was observed among these five cp genome sequences in the IR/SC boundary regions. Variation in insertions and deletions were observed in the cp genomes of the five species over three different intervals, and a large number of single-nucleotide polymorphism variants were detected in the rps3-rpl22-rps19 region. Phylogenetic analysis of complete cp genome sequences revealed the evolutionary relationships among 23 Zanthoxylum species (29 samples).ConclusionComparative analysis revealed that rps3-rpl22-rps19 is a highly variable divergent region in Zanthoxylum that could be developed as candidate markers for phylogenetic studies and species identification. This study identified a pair of molecular markers from hypervariable regions that can be used to distinguish between the five Zanthoxylum species and validated their utility. Overall, the results of this study provide new insights into the genetic breeding, germplasm exploration, and phylogeny of Zanthoxylum species.
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series Frontiers in Genetics
spelling doaj-art-092137d2c8b64520a0c27fe8064672be2024-12-24T06:36:50ZengFrontiers Media S.A.Frontiers in Genetics1664-80212024-12-011510.3389/fgene.2024.14958911495891Comparative chloroplast genome analysis of five widespread species (Zanthoxylum L.) and development of molecular markers for their discriminationChong Sun0Chong Sun1Huamin Liu2Yuan Guo3Xueqian Fu4Xinxin Zhu5Han Liu6Han Liu7Ning Tang8Zexiong Chen9Yiqing Liu10Yiqing Liu11Xia Liu12College of Horticulture and Gardening/Spicy Crops Research Institute, Yangtze University, Jingzhou, Hubei, ChinaCollege of Smart Agriculture, Chongqing University of Arts and Sciences, Chongqing, ChinaCollege of Smart Agriculture, Chongqing University of Arts and Sciences, Chongqing, ChinaCollege of Smart Agriculture, Chongqing University of Arts and Sciences, Chongqing, ChinaCollege of Smart Agriculture, Chongqing University of Arts and Sciences, Chongqing, ChinaCollege of Life Science, Xinyang Normal University, Xinyang, Henan, ChinaCollege of Smart Agriculture, Chongqing University of Arts and Sciences, Chongqing, ChinaCollege of Biology and Food Engineering, Chongqing Three Gorges University, Chongqing, ChinaCollege of Smart Agriculture, Chongqing University of Arts and Sciences, Chongqing, ChinaCollege of Smart Agriculture, Chongqing University of Arts and Sciences, Chongqing, ChinaCollege of Horticulture and Gardening/Spicy Crops Research Institute, Yangtze University, Jingzhou, Hubei, ChinaCollege of Smart Agriculture, Chongqing University of Arts and Sciences, Chongqing, ChinaCollege of Smart Agriculture, Chongqing University of Arts and Sciences, Chongqing, ChinaBackgroundZanthoxylum L., an important genus in the Rutaceae family, has great edible and medical values. However, the high degree of morphological similarity among Zanthoxylum species and the lack of sufficient chloroplast (cp) genomic resources have greatly impeded germplasm identification and phylogenetic analyses of Zanthoxylum.MethodsHere we assembled cp genomes of five widespread species (Zanthoxylum bungeanum, Z. armatum, Z. nitidum, Z. ailanthoides and Z. piasezkii) in China as a case study, comparative analysis of these assembled cp genomes.ResultsEach of them, ranging from 157,231 to 158,728 bp, has a quadripartite structure. Except for one extra gene in Z. piasezkii, 132 genes were identified in each species, including 87 encode protein genes, 37 transfer ribose nucleic acid (tRNA) genes, and eight ribosomal RNA (rRNA) genes. Substantial variation was observed among these five cp genome sequences in the IR/SC boundary regions. Variation in insertions and deletions were observed in the cp genomes of the five species over three different intervals, and a large number of single-nucleotide polymorphism variants were detected in the rps3-rpl22-rps19 region. Phylogenetic analysis of complete cp genome sequences revealed the evolutionary relationships among 23 Zanthoxylum species (29 samples).ConclusionComparative analysis revealed that rps3-rpl22-rps19 is a highly variable divergent region in Zanthoxylum that could be developed as candidate markers for phylogenetic studies and species identification. This study identified a pair of molecular markers from hypervariable regions that can be used to distinguish between the five Zanthoxylum species and validated their utility. Overall, the results of this study provide new insights into the genetic breeding, germplasm exploration, and phylogeny of Zanthoxylum species.https://www.frontiersin.org/articles/10.3389/fgene.2024.1495891/fullzanthoxylumcomplete chloroplast genomephylogenyspecies discrimination zanthoxylumspecies discriminationmolecular markers
spellingShingle Chong Sun
Chong Sun
Huamin Liu
Yuan Guo
Xueqian Fu
Xinxin Zhu
Han Liu
Han Liu
Ning Tang
Zexiong Chen
Yiqing Liu
Yiqing Liu
Xia Liu
Comparative chloroplast genome analysis of five widespread species (Zanthoxylum L.) and development of molecular markers for their discrimination
Frontiers in Genetics
zanthoxylum
complete chloroplast genome
phylogeny
species discrimination zanthoxylum
species discrimination
molecular markers
title Comparative chloroplast genome analysis of five widespread species (Zanthoxylum L.) and development of molecular markers for their discrimination
title_full Comparative chloroplast genome analysis of five widespread species (Zanthoxylum L.) and development of molecular markers for their discrimination
title_fullStr Comparative chloroplast genome analysis of five widespread species (Zanthoxylum L.) and development of molecular markers for their discrimination
title_full_unstemmed Comparative chloroplast genome analysis of five widespread species (Zanthoxylum L.) and development of molecular markers for their discrimination
title_short Comparative chloroplast genome analysis of five widespread species (Zanthoxylum L.) and development of molecular markers for their discrimination
title_sort comparative chloroplast genome analysis of five widespread species zanthoxylum l and development of molecular markers for their discrimination
topic zanthoxylum
complete chloroplast genome
phylogeny
species discrimination zanthoxylum
species discrimination
molecular markers
url https://www.frontiersin.org/articles/10.3389/fgene.2024.1495891/full
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