Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes
Our aim was to evaluate the long-term efficacy and safety of percutaneous transhepatic obliteration (PTO) alone and combined with balloon-occluded retrograde transvenous obliteration (BRTO) for gastroesophageal varices refractory to BRTO alone. Between July 1999 and December 2010, 13 patients with g...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/498535 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850231886645821440 |
|---|---|
| author | Fumio Uchiyama Satoru Murata Shiro Onozawa Ken Nakazawa Fumie Sugihara Daisuke Yasui Yoshiyuki Narahara Eiji Uchida Yasuo Amano Shin-ichiro Kumita |
| author_facet | Fumio Uchiyama Satoru Murata Shiro Onozawa Ken Nakazawa Fumie Sugihara Daisuke Yasui Yoshiyuki Narahara Eiji Uchida Yasuo Amano Shin-ichiro Kumita |
| author_sort | Fumio Uchiyama |
| collection | DOAJ |
| description | Our aim was to evaluate the long-term efficacy and safety of percutaneous transhepatic obliteration (PTO) alone and combined with balloon-occluded retrograde transvenous obliteration (BRTO) for gastroesophageal varices refractory to BRTO alone. Between July 1999 and December 2010, 13 patients with gastroesophageal varices refractory to BRTO were treated with PTO (n = 6) or a combination of PTO and BRTO (n = 7). We retrospectively investigated the rates of survival, recurrence, or worsening of the varices; hepatic function before and after the procedure; and complications. The procedure achieved complete obliteration or significant reduction of the varices in all 13 patients without major complications. During follow-up, the varices had recurred in 2 patients, of which one had hepatocellular carcinoma, and the other died suddenly from variceal rebleeding 7 years after PTO. The remaining 11 patients did not experience worsening of the varices and showed significant improvements in the serum ammonia levels and prothrombin time. The mean follow-up period was 90 months, and the cumulative survival rate at 1, 3, and 5 years was 92.9%, 85.7%, and 85.7%, respectively. Both PTO and combined PTO and BRTO seem as safe and effective procedures for the treatment of gastroesophageal varices refractory to BRTO alone. |
| format | Article |
| id | doaj-art-091d3d83d07e4a1cb7f35b7d8e146435 |
| institution | OA Journals |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-091d3d83d07e4a1cb7f35b7d8e1464352025-08-20T02:03:24ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/498535498535Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and OutcomesFumio Uchiyama0Satoru Murata1Shiro Onozawa2Ken Nakazawa3Fumie Sugihara4Daisuke Yasui5Yoshiyuki Narahara6Eiji Uchida7Yasuo Amano8Shin-ichiro Kumita9Department of Radiology, Nippon Medical School, 1-1-5 Sendagi, Center for Advanced Medical Technology, Bunkyou-ku, Tokyo 113-8603, JapanDepartment of Radiology, Nippon Medical School, 1-1-5 Sendagi, Center for Advanced Medical Technology, Bunkyou-ku, Tokyo 113-8603, JapanDepartment of Radiology, Nippon Medical School, 1-1-5 Sendagi, Center for Advanced Medical Technology, Bunkyou-ku, Tokyo 113-8603, JapanDepartment of Radiology, Nippon Medical School, 1-1-5 Sendagi, Center for Advanced Medical Technology, Bunkyou-ku, Tokyo 113-8603, JapanDepartment of Radiology, Nippon Medical School, 1-1-5 Sendagi, Center for Advanced Medical Technology, Bunkyou-ku, Tokyo 113-8603, JapanDepartment of Radiology, Nippon Medical School, 1-1-5 Sendagi, Center for Advanced Medical Technology, Bunkyou-ku, Tokyo 113-8603, JapanDivision of Gastroenterology, Department of Internal Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyou-ku, Tokyo 113-8603, JapanDepartment of Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyou-ku, Tokyo 113-8603, JapanDepartment of Radiology, Nippon Medical School, 1-1-5 Sendagi, Center for Advanced Medical Technology, Bunkyou-ku, Tokyo 113-8603, JapanDepartment of Radiology, Nippon Medical School, 1-1-5 Sendagi, Center for Advanced Medical Technology, Bunkyou-ku, Tokyo 113-8603, JapanOur aim was to evaluate the long-term efficacy and safety of percutaneous transhepatic obliteration (PTO) alone and combined with balloon-occluded retrograde transvenous obliteration (BRTO) for gastroesophageal varices refractory to BRTO alone. Between July 1999 and December 2010, 13 patients with gastroesophageal varices refractory to BRTO were treated with PTO (n = 6) or a combination of PTO and BRTO (n = 7). We retrospectively investigated the rates of survival, recurrence, or worsening of the varices; hepatic function before and after the procedure; and complications. The procedure achieved complete obliteration or significant reduction of the varices in all 13 patients without major complications. During follow-up, the varices had recurred in 2 patients, of which one had hepatocellular carcinoma, and the other died suddenly from variceal rebleeding 7 years after PTO. The remaining 11 patients did not experience worsening of the varices and showed significant improvements in the serum ammonia levels and prothrombin time. The mean follow-up period was 90 months, and the cumulative survival rate at 1, 3, and 5 years was 92.9%, 85.7%, and 85.7%, respectively. Both PTO and combined PTO and BRTO seem as safe and effective procedures for the treatment of gastroesophageal varices refractory to BRTO alone.http://dx.doi.org/10.1155/2013/498535 |
| spellingShingle | Fumio Uchiyama Satoru Murata Shiro Onozawa Ken Nakazawa Fumie Sugihara Daisuke Yasui Yoshiyuki Narahara Eiji Uchida Yasuo Amano Shin-ichiro Kumita Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes The Scientific World Journal |
| title | Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes |
| title_full | Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes |
| title_fullStr | Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes |
| title_full_unstemmed | Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes |
| title_short | Management of Gastric Varices Unsuccessfully Treated by Balloon-Occluded Retrograde Transvenous Obliteration: Long-Term Follow-Up and Outcomes |
| title_sort | management of gastric varices unsuccessfully treated by balloon occluded retrograde transvenous obliteration long term follow up and outcomes |
| url | http://dx.doi.org/10.1155/2013/498535 |
| work_keys_str_mv | AT fumiouchiyama managementofgastricvaricesunsuccessfullytreatedbyballoonoccludedretrogradetransvenousobliterationlongtermfollowupandoutcomes AT satorumurata managementofgastricvaricesunsuccessfullytreatedbyballoonoccludedretrogradetransvenousobliterationlongtermfollowupandoutcomes AT shiroonozawa managementofgastricvaricesunsuccessfullytreatedbyballoonoccludedretrogradetransvenousobliterationlongtermfollowupandoutcomes AT kennakazawa managementofgastricvaricesunsuccessfullytreatedbyballoonoccludedretrogradetransvenousobliterationlongtermfollowupandoutcomes AT fumiesugihara managementofgastricvaricesunsuccessfullytreatedbyballoonoccludedretrogradetransvenousobliterationlongtermfollowupandoutcomes AT daisukeyasui managementofgastricvaricesunsuccessfullytreatedbyballoonoccludedretrogradetransvenousobliterationlongtermfollowupandoutcomes AT yoshiyukinarahara managementofgastricvaricesunsuccessfullytreatedbyballoonoccludedretrogradetransvenousobliterationlongtermfollowupandoutcomes AT eijiuchida managementofgastricvaricesunsuccessfullytreatedbyballoonoccludedretrogradetransvenousobliterationlongtermfollowupandoutcomes AT yasuoamano managementofgastricvaricesunsuccessfullytreatedbyballoonoccludedretrogradetransvenousobliterationlongtermfollowupandoutcomes AT shinichirokumita managementofgastricvaricesunsuccessfullytreatedbyballoonoccludedretrogradetransvenousobliterationlongtermfollowupandoutcomes |