Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses
We summarized the most recent findings on the role of autophagy in antiviral immune response. We described how viruses have developed strategies to subvert the autophagic process. A particular attention has been given to Epstein-Barr and Kaposi’s sarcoma associated Herpesvirus, viruses studied for m...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2015/546063 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832555901950623744 |
|---|---|
| author | Roberta Santarelli Marisa Granato Alberto Faggioni Mara Cirone |
| author_facet | Roberta Santarelli Marisa Granato Alberto Faggioni Mara Cirone |
| author_sort | Roberta Santarelli |
| collection | DOAJ |
| description | We summarized the most recent findings on the role of autophagy in antiviral immune response. We described how viruses have developed strategies to subvert the autophagic process. A particular attention has been given to Epstein-Barr and Kaposi’s sarcoma associated Herpesvirus, viruses studied for many years in our laboratory. These two viruses belong to γ-Herpesvirus subfamily and are associated with several human cancers. Besides the effects on the immune response, we have described how autophagy subversion by viruses may also concur to the enhancement of their replication and to viral tumorigenesis. |
| format | Article |
| id | doaj-art-0918a9a128ab478ba5a0d2bc9f404ef1 |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-0918a9a128ab478ba5a0d2bc9f404ef12025-02-03T05:46:54ZengWileyJournal of Immunology Research2314-88612314-71562015-01-01201510.1155/2015/546063546063Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma HerpesvirusesRoberta Santarelli0Marisa Granato1Alberto Faggioni2Mara Cirone3Department of Experimental Medicine, “Sapienza” University of Rome, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Experimental Medicine, “Sapienza” University of Rome, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Experimental Medicine, “Sapienza” University of Rome, Viale Regina Elena 324, 00161 Rome, ItalyDepartment of Experimental Medicine, “Sapienza” University of Rome, Viale Regina Elena 324, 00161 Rome, ItalyWe summarized the most recent findings on the role of autophagy in antiviral immune response. We described how viruses have developed strategies to subvert the autophagic process. A particular attention has been given to Epstein-Barr and Kaposi’s sarcoma associated Herpesvirus, viruses studied for many years in our laboratory. These two viruses belong to γ-Herpesvirus subfamily and are associated with several human cancers. Besides the effects on the immune response, we have described how autophagy subversion by viruses may also concur to the enhancement of their replication and to viral tumorigenesis.http://dx.doi.org/10.1155/2015/546063 |
| spellingShingle | Roberta Santarelli Marisa Granato Alberto Faggioni Mara Cirone Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses Journal of Immunology Research |
| title | Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses |
| title_full | Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses |
| title_fullStr | Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses |
| title_full_unstemmed | Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses |
| title_short | Interference with the Autophagic Process as a Viral Strategy to Escape from the Immune Control: Lesson from Gamma Herpesviruses |
| title_sort | interference with the autophagic process as a viral strategy to escape from the immune control lesson from gamma herpesviruses |
| url | http://dx.doi.org/10.1155/2015/546063 |
| work_keys_str_mv | AT robertasantarelli interferencewiththeautophagicprocessasaviralstrategytoescapefromtheimmunecontrollessonfromgammaherpesviruses AT marisagranato interferencewiththeautophagicprocessasaviralstrategytoescapefromtheimmunecontrollessonfromgammaherpesviruses AT albertofaggioni interferencewiththeautophagicprocessasaviralstrategytoescapefromtheimmunecontrollessonfromgammaherpesviruses AT maracirone interferencewiththeautophagicprocessasaviralstrategytoescapefromtheimmunecontrollessonfromgammaherpesviruses |