Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges
Malignant growth is expected to surpass other significant causes of death as one of the top reasons for dismalness and mortality worldwide. According to a World Health Organization (WHO) study, this illness causes approximately between 9 and 10 million instances of deaths annually. Chemotherapy, rad...
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| author | Rachitha Puttasiddaiah Nagaraj Basavegowda Nityashree Kyathegowdanadoddi Lakshmanagowda Vinay Basavegowda Raghavendra Niju Sagar Kandi Sridhar Praveen Kumar Dikkala Maharshi Bhaswant Kwang-Hyun Baek Minaxi Sharma |
| author_facet | Rachitha Puttasiddaiah Nagaraj Basavegowda Nityashree Kyathegowdanadoddi Lakshmanagowda Vinay Basavegowda Raghavendra Niju Sagar Kandi Sridhar Praveen Kumar Dikkala Maharshi Bhaswant Kwang-Hyun Baek Minaxi Sharma |
| author_sort | Rachitha Puttasiddaiah |
| collection | DOAJ |
| description | Malignant growth is expected to surpass other significant causes of death as one of the top reasons for dismalness and mortality worldwide. According to a World Health Organization (WHO) study, this illness causes approximately between 9 and 10 million instances of deaths annually. Chemotherapy, radiation, and surgery are the three main methods of treating cancer. These methods seek to completely eradicate all cancer cells while having the fewest possible unintended impacts on healthy cell types. Owing to the lack of target selectivity, the majority of medications have substantial side effects. On the other hand, nanomaterials have transformed the identification, diagnosis, and management of cancer. Nanostructures with biomimetic properties have been grown as of late, fully intent on observing and treating the sickness. These nanostructures are expected to be consumed by growth in areas with profound disease. Furthermore, because of their extraordinary physicochemical properties, which incorporate nanoscale aspects, a more prominent surface region, explicit geometrical features, and the ability to embody different substances within or on their outside surfaces, nanostructures are remarkable nano-vehicles for conveying restorative specialists to their designated regions. This review discusses recent developments in nanostructured materials such as graphene, dendrimers, cell-penetrating peptide nanoparticles, nanoliposomes, lipid nanoparticles, magnetic nanoparticles, and nano-omics in the diagnosis and management of cancer. |
| format | Article |
| id | doaj-art-090d43856dde4a23ad1f945df5792553 |
| institution | Kabale University |
| issn | 1999-4923 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj-art-090d43856dde4a23ad1f945df57925532025-01-24T13:45:49ZengMDPI AGPharmaceutics1999-49232025-01-011717010.3390/pharmaceutics17010070Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and ChallengesRachitha Puttasiddaiah0Nagaraj Basavegowda1Nityashree Kyathegowdanadoddi Lakshmanagowda2Vinay Basavegowda Raghavendra3Niju Sagar4Kandi Sridhar5Praveen Kumar Dikkala6Maharshi Bhaswant7Kwang-Hyun Baek8Minaxi Sharma9Teresian College Research Centre, Teresian College, Siddarthanagar, Mysore 570011, IndiaDepartment of Biotechnology, Yeungnam University, Gyeongsan 38541, Republic of KoreaSchool of Psychological Sciences, Christ University, Bangalore 560073, IndiaTeresian College Research Centre, Teresian College, Siddarthanagar, Mysore 570011, IndiaTeresian College Research Centre, Teresian College, Siddarthanagar, Mysore 570011, IndiaDepartment of Food Technology, Karpagam Academy of Higher Education (Deemed to be University), Coimbatore 641021, IndiaDepartment of Food Technology, Koneru Lakshmaiah Education Foundation, Vaddeswaram 522502, IndiaNew Industry Creation Hatchery Center, Tohoku University, Sendai 9808579, JapanDepartment of Biotechnology, Yeungnam University, Gyeongsan 38541, Republic of KoreaResearch Centre for Life Science and Healthcare, Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute (CBI), University of Nottingham Ningbo China, Ningbo 315000, ChinaMalignant growth is expected to surpass other significant causes of death as one of the top reasons for dismalness and mortality worldwide. According to a World Health Organization (WHO) study, this illness causes approximately between 9 and 10 million instances of deaths annually. Chemotherapy, radiation, and surgery are the three main methods of treating cancer. These methods seek to completely eradicate all cancer cells while having the fewest possible unintended impacts on healthy cell types. Owing to the lack of target selectivity, the majority of medications have substantial side effects. On the other hand, nanomaterials have transformed the identification, diagnosis, and management of cancer. Nanostructures with biomimetic properties have been grown as of late, fully intent on observing and treating the sickness. These nanostructures are expected to be consumed by growth in areas with profound disease. Furthermore, because of their extraordinary physicochemical properties, which incorporate nanoscale aspects, a more prominent surface region, explicit geometrical features, and the ability to embody different substances within or on their outside surfaces, nanostructures are remarkable nano-vehicles for conveying restorative specialists to their designated regions. This review discusses recent developments in nanostructured materials such as graphene, dendrimers, cell-penetrating peptide nanoparticles, nanoliposomes, lipid nanoparticles, magnetic nanoparticles, and nano-omics in the diagnosis and management of cancer.https://www.mdpi.com/1999-4923/17/1/70nano-oncologynano-omicsgraphenedendrimerslipid nanoparticles |
| spellingShingle | Rachitha Puttasiddaiah Nagaraj Basavegowda Nityashree Kyathegowdanadoddi Lakshmanagowda Vinay Basavegowda Raghavendra Niju Sagar Kandi Sridhar Praveen Kumar Dikkala Maharshi Bhaswant Kwang-Hyun Baek Minaxi Sharma Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges Pharmaceutics nano-oncology nano-omics graphene dendrimers lipid nanoparticles |
| title | Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges |
| title_full | Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges |
| title_fullStr | Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges |
| title_full_unstemmed | Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges |
| title_short | Emerging Nanoparticle-Based Diagnostics and Therapeutics for Cancer: Innovations and Challenges |
| title_sort | emerging nanoparticle based diagnostics and therapeutics for cancer innovations and challenges |
| topic | nano-oncology nano-omics graphene dendrimers lipid nanoparticles |
| url | https://www.mdpi.com/1999-4923/17/1/70 |
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