Modified Fluid Gelatin Versus Crystalloids in CABG Surgery Patients: a Propensity Score Matched Analysis
The objective: to compare efficacy and safety of infusion therapy with modified fluid gelatin (MFG) and balanced salt solutions.Subjects and Methods. 1,820 patients after coronary artery bypass grafting were enrolled in the retrospective study. Two groups of 362 patients were formed by the matching...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2022-07-01
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| Series: | Вестник анестезиологии и реаниматологии |
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| Online Access: | https://www.vair-journal.com/jour/article/view/675 |
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| author | V. V. Bazylev A. I. Magilevetz A. A. Schegolkov A. V. Bulygin |
| author_facet | V. V. Bazylev A. I. Magilevetz A. A. Schegolkov A. V. Bulygin |
| author_sort | V. V. Bazylev |
| collection | DOAJ |
| description | The objective: to compare efficacy and safety of infusion therapy with modified fluid gelatin (MFG) and balanced salt solutions.Subjects and Methods. 1,820 patients after coronary artery bypass grafting were enrolled in the retrospective study. Two groups of 362 patients were formed by the matching index method.Results. Primary endpoints. Acute kidney injury (AKI) developed less frequently in the crystalloid group compared to the colloid group, also more patients in the colloid group received fresh frozen plasma and red blood cells.In the crystalloid group, the duration of stay in the intensive care unit (ICU) decreased, while the duration of mechanical ventilation increased. The use of MFG within infusion therapy made it possible to reduce the volume of balanced salt solutions transfused both in the perioperative period and during stay in the intensive care unit. However, there was no intergroup difference in the total volume of infusion therapy calculated based on the patient's actual weight.Conclusions. The use of MFG as part of infusion therapy may increase the incidence of AKI, the need for transfusion of blood components, as well as the duration of stay in ICU. Use of MFG was associated with shorter duration of mechanical ventilation. |
| format | Article |
| id | doaj-art-08fd19863bbd41cb82a79cc6bd03f75e |
| institution | Kabale University |
| issn | 2078-5658 2541-8653 |
| language | Russian |
| publishDate | 2022-07-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Вестник анестезиологии и реаниматологии |
| spelling | doaj-art-08fd19863bbd41cb82a79cc6bd03f75e2025-08-20T03:56:32ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532022-07-01193667410.21292/2078-5658-2022-19-3-66-74528Modified Fluid Gelatin Versus Crystalloids in CABG Surgery Patients: a Propensity Score Matched AnalysisV. V. Bazylev0A. I. Magilevetz1A. A. Schegolkov2A. V. Bulygin3Federal Center of Cardiovascular SurgeryFederal Center of Cardiovascular SurgeryFederal Center of Cardiovascular SurgeryFederal Center of Cardiovascular SurgeryThe objective: to compare efficacy and safety of infusion therapy with modified fluid gelatin (MFG) and balanced salt solutions.Subjects and Methods. 1,820 patients after coronary artery bypass grafting were enrolled in the retrospective study. Two groups of 362 patients were formed by the matching index method.Results. Primary endpoints. Acute kidney injury (AKI) developed less frequently in the crystalloid group compared to the colloid group, also more patients in the colloid group received fresh frozen plasma and red blood cells.In the crystalloid group, the duration of stay in the intensive care unit (ICU) decreased, while the duration of mechanical ventilation increased. The use of MFG within infusion therapy made it possible to reduce the volume of balanced salt solutions transfused both in the perioperative period and during stay in the intensive care unit. However, there was no intergroup difference in the total volume of infusion therapy calculated based on the patient's actual weight.Conclusions. The use of MFG as part of infusion therapy may increase the incidence of AKI, the need for transfusion of blood components, as well as the duration of stay in ICU. Use of MFG was associated with shorter duration of mechanical ventilation.https://www.vair-journal.com/jour/article/view/675acute kidney injuryfresh frozen plasmared blood cell massmodified liquid gelatinsynthetic colloidsbalance |
| spellingShingle | V. V. Bazylev A. I. Magilevetz A. A. Schegolkov A. V. Bulygin Modified Fluid Gelatin Versus Crystalloids in CABG Surgery Patients: a Propensity Score Matched Analysis Вестник анестезиологии и реаниматологии acute kidney injury fresh frozen plasma red blood cell mass modified liquid gelatin synthetic colloids balance |
| title | Modified Fluid Gelatin Versus Crystalloids in CABG Surgery Patients: a Propensity Score Matched Analysis |
| title_full | Modified Fluid Gelatin Versus Crystalloids in CABG Surgery Patients: a Propensity Score Matched Analysis |
| title_fullStr | Modified Fluid Gelatin Versus Crystalloids in CABG Surgery Patients: a Propensity Score Matched Analysis |
| title_full_unstemmed | Modified Fluid Gelatin Versus Crystalloids in CABG Surgery Patients: a Propensity Score Matched Analysis |
| title_short | Modified Fluid Gelatin Versus Crystalloids in CABG Surgery Patients: a Propensity Score Matched Analysis |
| title_sort | modified fluid gelatin versus crystalloids in cabg surgery patients a propensity score matched analysis |
| topic | acute kidney injury fresh frozen plasma red blood cell mass modified liquid gelatin synthetic colloids balance |
| url | https://www.vair-journal.com/jour/article/view/675 |
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