Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook

BackgroundArtificial intelligence (AI) has emerged as a transformative tool in oncology, offering promising applications in chemotherapy development, cancer diagnosis, and predicting chemotherapy response. Despite its potential, debates persist regarding the predictive accuracy of AI technologies, p...

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Main Authors: Bassam Abdul Rasool Hassan, Ali Haider Mohammed, Souheil Hallit, Diana Malaeb, Hassan Hosseini
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1475893/full
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author Bassam Abdul Rasool Hassan
Ali Haider Mohammed
Souheil Hallit
Souheil Hallit
Souheil Hallit
Diana Malaeb
Hassan Hosseini
Hassan Hosseini
author_facet Bassam Abdul Rasool Hassan
Ali Haider Mohammed
Souheil Hallit
Souheil Hallit
Souheil Hallit
Diana Malaeb
Hassan Hosseini
Hassan Hosseini
author_sort Bassam Abdul Rasool Hassan
collection DOAJ
description BackgroundArtificial intelligence (AI) has emerged as a transformative tool in oncology, offering promising applications in chemotherapy development, cancer diagnosis, and predicting chemotherapy response. Despite its potential, debates persist regarding the predictive accuracy of AI technologies, particularly machine learning (ML) and deep learning (DL).ObjectiveThis review aims to explore the role of AI in forecasting outcomes related to chemotherapy development, cancer diagnosis, and treatment response, synthesizing current advancements and identifying critical gaps in the field.MethodsA comprehensive literature search was conducted across PubMed, Embase, Web of Science, and Cochrane databases up to 2023. Keywords included “Artificial Intelligence (AI),” “Machine Learning (ML),” and “Deep Learning (DL)” combined with “chemotherapy development,” “cancer diagnosis,” and “cancer treatment.” Articles published within the last four years and written in English were included. The Prediction Model Risk of Bias Assessment tool was utilized to assess the risk of bias in the selected studies.ConclusionThis review underscores the substantial impact of AI, including ML and DL, on cancer diagnosis, chemotherapy innovation, and treatment response for both solid and hematological tumors. Evidence from recent studies highlights AI’s potential to reduce cancer-related mortality by optimizing diagnostic accuracy, personalizing treatment plans, and improving therapeutic outcomes. Future research should focus on addressing challenges in clinical implementation, ethical considerations, and scalability to enhance AI’s integration into oncology care.
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spelling doaj-art-08f44493d9534d9dbe478a5bdc3407d12025-02-07T13:48:57ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-02-011510.3389/fonc.2025.14758931475893Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlookBassam Abdul Rasool Hassan0Ali Haider Mohammed1Souheil Hallit2Souheil Hallit3Souheil Hallit4Diana Malaeb5Hassan Hosseini6Hassan Hosseini7Department of Pharmacy, Al Rafidain University College, Baghdad, IraqSchool of Pharmacy, Monash University Malaysia, Subang Jaya, MalaysiaSchool of Medicine and Medical Sciences, Holy Spirit University of Kaslik, Jounieh, LebanonDepartment of Psychology, College of Humanities, Effat University, Jeddah, Saudi ArabiaApplied Science Research Center, Applied Science Private University, Amman, JordanCollege of Pharmacy, Gulf Medical University, Ajman, United Arab EmiratesInstitut Coeur et Cerveau de l’Est Parisien (ICCE), UPEC-University Paris-Est, Creteil, FranceRAMSAY SANTÉ, Hôpital Paul D’Egine (HPPE), Champigny sur Marne, FranceBackgroundArtificial intelligence (AI) has emerged as a transformative tool in oncology, offering promising applications in chemotherapy development, cancer diagnosis, and predicting chemotherapy response. Despite its potential, debates persist regarding the predictive accuracy of AI technologies, particularly machine learning (ML) and deep learning (DL).ObjectiveThis review aims to explore the role of AI in forecasting outcomes related to chemotherapy development, cancer diagnosis, and treatment response, synthesizing current advancements and identifying critical gaps in the field.MethodsA comprehensive literature search was conducted across PubMed, Embase, Web of Science, and Cochrane databases up to 2023. Keywords included “Artificial Intelligence (AI),” “Machine Learning (ML),” and “Deep Learning (DL)” combined with “chemotherapy development,” “cancer diagnosis,” and “cancer treatment.” Articles published within the last four years and written in English were included. The Prediction Model Risk of Bias Assessment tool was utilized to assess the risk of bias in the selected studies.ConclusionThis review underscores the substantial impact of AI, including ML and DL, on cancer diagnosis, chemotherapy innovation, and treatment response for both solid and hematological tumors. Evidence from recent studies highlights AI’s potential to reduce cancer-related mortality by optimizing diagnostic accuracy, personalizing treatment plans, and improving therapeutic outcomes. Future research should focus on addressing challenges in clinical implementation, ethical considerations, and scalability to enhance AI’s integration into oncology care.https://www.frontiersin.org/articles/10.3389/fonc.2025.1475893/fullartificial intelligence (AI)machine learning (ML)deep learning (DL)chemotherapy developmentcancer diagnosiscancer treatment
spellingShingle Bassam Abdul Rasool Hassan
Ali Haider Mohammed
Souheil Hallit
Souheil Hallit
Souheil Hallit
Diana Malaeb
Hassan Hosseini
Hassan Hosseini
Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook
Frontiers in Oncology
artificial intelligence (AI)
machine learning (ML)
deep learning (DL)
chemotherapy development
cancer diagnosis
cancer treatment
title Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook
title_full Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook
title_fullStr Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook
title_full_unstemmed Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook
title_short Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook
title_sort exploring the role of artificial intelligence in chemotherapy development cancer diagnosis and treatment present achievements and future outlook
topic artificial intelligence (AI)
machine learning (ML)
deep learning (DL)
chemotherapy development
cancer diagnosis
cancer treatment
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1475893/full
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