Causal links between obesity, lipids, adipokines, and cognition: a bidirectional Mendelian-randomization analysis

Causal links between obesity, lipids, adipokines, and cognition: a bidirectional Mendelian-randomization analysis

BackgroundThe aim of this study was to explore the genetic level association between obesity, lipids, adipokines, and cognitive ability using bidirectional Mendelian randomization (MR) strategies.MethodsSummary data for three obesity indicators [body mass index (BMI), body fat percentage (BFP) and w...

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Bibliographic Details
Main Authors: Meng Gong, Haichao Liu, Zhixiang Liu, Yongshen Wang, Shiyi Qi, Hong Guo, Song Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Endocrinology
Subjects:
adipokines
bidirectional
cognitive ability
genetic correlation
lipids
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1439341/full
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