Physical exercise as a key to activating fat burning through the activation of uncoupling protein 1 (ucp1) in adipose tissue: a scoping review

Background: In addition to being an important element related to thermogenesis, exercise is an excellent intervention to reduce obesity. Recent research indicates that "exerkines," or chemicals released during physical activity, can change the Brown adipose tissue (BAT) activation and whi...

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Main Authors: Dany Pramuno Putra, Junian Cahyanto Wibawa, Baskoro Nugroho Putro
Format: Article
Language:English
Published: FEADEF 2025-04-01
Series:Retos: Nuevas Tendencias en Educación Física, Deportes y Recreación
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Online Access:https://recyt.fecyt.es/index.php/retos/article/view/114284
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author Dany Pramuno Putra
Junian Cahyanto Wibawa
Baskoro Nugroho Putro
author_facet Dany Pramuno Putra
Junian Cahyanto Wibawa
Baskoro Nugroho Putro
author_sort Dany Pramuno Putra
collection DOAJ
description Background: In addition to being an important element related to thermogenesis, exercise is an excellent intervention to reduce obesity. Recent research indicates that "exerkines," or chemicals released during physical activity, can change the Brown adipose tissue (BAT) activation and white adipose tissue browning. The compound processes by which BAT activation is affected by peripheral variables brought on by exercise, however, are not well understood. Moreover, the impact effect physical activity on BAT activation is not well understood. One important protein in charge of both white and brown adipose tissue exhibit adaptive thermogenesis going through browning is Uncoupling Protein 1 (UCP1). Objective: This study aims to analyze the effect of physical exercise on increasing uncoupling protein 1 (UCP1) in mice. Materials and methods: We looked through a number of literature databases for our systematic review investigation, including Pubmed, Web of Science, and Science Direct. articles that addressed physical activity and UCP1 that were released within the last five years. The Web of Science, Pubmed, and Science Direct databases were used to locate 380 published articles. For this systematic review, ten papers that met the inclusion criteria were selected and reviewed. Systematic Reviews and Meta-Analyses' Preferred Reporting Items (PRISMA) were used in this study to assess standard operating procedures. Results: The findings of this study indicate that physical exercise has been shown to increase UCP1 expression. Conclusions: It has been demonstrated that physical activity increases UCP1 expression. The process of boosting metabolism and thermogenesis will be triggered by this rise. in order for the energy expenditure generated by adipose tissue to increase.
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spelling doaj-art-08f10204828d46fc87473640ab5bb5dd2025-08-20T02:09:09ZengFEADEFRetos: Nuevas Tendencias en Educación Física, Deportes y Recreación1579-17261988-20412025-04-016610.47197/retos.v66.114284Physical exercise as a key to activating fat burning through the activation of uncoupling protein 1 (ucp1) in adipose tissue: a scoping reviewDany Pramuno Putra0Junian Cahyanto Wibawa1Baskoro Nugroho Putro2Universitas AirlanggaSTKIP PGRI TrenggalekUniversitas Sebelas Maret Background: In addition to being an important element related to thermogenesis, exercise is an excellent intervention to reduce obesity. Recent research indicates that "exerkines," or chemicals released during physical activity, can change the Brown adipose tissue (BAT) activation and white adipose tissue browning. The compound processes by which BAT activation is affected by peripheral variables brought on by exercise, however, are not well understood. Moreover, the impact effect physical activity on BAT activation is not well understood. One important protein in charge of both white and brown adipose tissue exhibit adaptive thermogenesis going through browning is Uncoupling Protein 1 (UCP1). Objective: This study aims to analyze the effect of physical exercise on increasing uncoupling protein 1 (UCP1) in mice. Materials and methods: We looked through a number of literature databases for our systematic review investigation, including Pubmed, Web of Science, and Science Direct. articles that addressed physical activity and UCP1 that were released within the last five years. The Web of Science, Pubmed, and Science Direct databases were used to locate 380 published articles. For this systematic review, ten papers that met the inclusion criteria were selected and reviewed. Systematic Reviews and Meta-Analyses' Preferred Reporting Items (PRISMA) were used in this study to assess standard operating procedures. Results: The findings of this study indicate that physical exercise has been shown to increase UCP1 expression. Conclusions: It has been demonstrated that physical activity increases UCP1 expression. The process of boosting metabolism and thermogenesis will be triggered by this rise. in order for the energy expenditure generated by adipose tissue to increase. https://recyt.fecyt.es/index.php/retos/article/view/114284Physical exercisephysical fitnessss batucp1 fatty acid
spellingShingle Dany Pramuno Putra
Junian Cahyanto Wibawa
Baskoro Nugroho Putro
Physical exercise as a key to activating fat burning through the activation of uncoupling protein 1 (ucp1) in adipose tissue: a scoping review
Retos: Nuevas Tendencias en Educación Física, Deportes y Recreación
Physical exercise
physical fitness
ss
bat
ucp1
fatty acid
title Physical exercise as a key to activating fat burning through the activation of uncoupling protein 1 (ucp1) in adipose tissue: a scoping review
title_full Physical exercise as a key to activating fat burning through the activation of uncoupling protein 1 (ucp1) in adipose tissue: a scoping review
title_fullStr Physical exercise as a key to activating fat burning through the activation of uncoupling protein 1 (ucp1) in adipose tissue: a scoping review
title_full_unstemmed Physical exercise as a key to activating fat burning through the activation of uncoupling protein 1 (ucp1) in adipose tissue: a scoping review
title_short Physical exercise as a key to activating fat burning through the activation of uncoupling protein 1 (ucp1) in adipose tissue: a scoping review
title_sort physical exercise as a key to activating fat burning through the activation of uncoupling protein 1 ucp1 in adipose tissue a scoping review
topic Physical exercise
physical fitness
ss
bat
ucp1
fatty acid
url https://recyt.fecyt.es/index.php/retos/article/view/114284
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