Physical exercise as a key to activating fat burning through the activation of uncoupling protein 1 (ucp1) in adipose tissue: a scoping review
Background: In addition to being an important element related to thermogenesis, exercise is an excellent intervention to reduce obesity. Recent research indicates that "exerkines," or chemicals released during physical activity, can change the Brown adipose tissue (BAT) activation and whi...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
FEADEF
2025-04-01
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| Series: | Retos: Nuevas Tendencias en Educación Física, Deportes y Recreación |
| Subjects: | |
| Online Access: | https://recyt.fecyt.es/index.php/retos/article/view/114284 |
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| Summary: | Background: In addition to being an important element related to thermogenesis, exercise is an excellent intervention to reduce obesity. Recent research indicates that "exerkines," or chemicals released during physical activity, can change the Brown adipose tissue (BAT) activation and white adipose tissue browning. The compound processes by which BAT activation is affected by peripheral variables brought on by exercise, however, are not well understood. Moreover, the impact effect physical activity on BAT activation is not well understood. One important protein in charge of both white and brown adipose tissue exhibit adaptive thermogenesis going through browning is Uncoupling Protein 1 (UCP1). Objective: This study aims to analyze the effect of physical exercise on increasing uncoupling protein 1 (UCP1) in mice.
Materials and methods: We looked through a number of literature databases for our systematic review investigation, including Pubmed, Web of Science, and Science Direct. articles that addressed physical activity and UCP1 that were released within the last five years. The Web of Science, Pubmed, and Science Direct databases were used to locate 380 published articles. For this systematic review, ten papers that met the inclusion criteria were selected and reviewed. Systematic Reviews and Meta-Analyses' Preferred Reporting Items (PRISMA) were used in this study to assess standard operating procedures.
Results: The findings of this study indicate that physical exercise has been shown to increase UCP1 expression.
Conclusions: It has been demonstrated that physical activity increases UCP1 expression. The process of boosting metabolism and thermogenesis will be triggered by this rise. in order for the energy expenditure generated by adipose tissue to increase.
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| ISSN: | 1579-1726 1988-2041 |