Pathogens and drug sensitivity analysis in 327 cases of peritoneal dialysis-related peritonitis

Objective To discuss the pathogens and drug resistance in continuous ambulatory peritoneal dialysis(CAPD)-related peritonitis.Methods The pathogens and drug resistance were retrospectively analyzed on 180 cases(327 cases/times) of CAPD-related peritonitis in our center from Jan2008 to May 2013.Resul...

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Main Authors: WANG Yiping, WANG Dong, WANG Li-yuan, JIN Hua, LIU Ling, MAO Yan-ping, LIU Jia-sheng
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2015-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57920949&Fpath=home&index=0
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author WANG Yiping
WANG Dong
WANG Li-yuan
JIN Hua
LIU Ling
MAO Yan-ping
LIU Jia-sheng
author_facet WANG Yiping
WANG Dong
WANG Li-yuan
JIN Hua
LIU Ling
MAO Yan-ping
LIU Jia-sheng
author_sort WANG Yiping
collection DOAJ
description Objective To discuss the pathogens and drug resistance in continuous ambulatory peritoneal dialysis(CAPD)-related peritonitis.Methods The pathogens and drug resistance were retrospectively analyzed on 180 cases(327 cases/times) of CAPD-related peritonitis in our center from Jan2008 to May 2013.Results Positive cultures were seen in 202 cases/times with culture positive rate being 61.77%.There were 154 cases/times of gram-positive cocci,including 123 cases/times(60.89%) of Staphylococcus aureus and coagulase-negative staphylococci.There were 38 cases/times of gram-negative bacilli,including 11 cases/times(5.45%) of E.coll There were 10 cases/times of fungi,including 7 cases/times(3.47%) of Candida.The drug-resistant rate of gram-positive bacteria to vancomycin was lowest(3.25%),followed by moxifloxacin(5.19%),rifampin(12.99%),gentamicin(35.71%) and levofloxacin(45.45%),and that to penicillin highest(84.42%).The drug-resistant rate of gram-negative bacteria to piperacillin/tazobactam was lowest(10.53%),followed by ceftazidime(23.68%),levofloxacin(26.32%),cefpiramide US(36.84%),and that to ampicillin/sulbactam was highest(50.00%).Of 54 cases of repeated infections(114 cases/times).72 cases/times were positive with the culture positive rate being 63.16%,including 63 cases/times of Gram-positive cocci,predominantly Staphylococcus aureus,accounting for 87.50%,and 9 cases/times of Gram-negative bacilli,predominantly Escherichia coli,accounting for 12.50%.The drug-resistant rate of Grampositive cocci to vancomycin was lowestCl.59%),followed by moxifloxacin(3.17%),levofloxacin(15.87%) and gentamicin(55.56%),and that to penicillin was highest(95.24%).The drug-resistant rate of Gram-negative bacilli to piperacillin/tazobactam was lowest(11.11%),followed by ceftazidime(22.22%),levofloxacin(33.33%),gentamicin(55.56%),and that to ampicillin/sulbactam was highest(88.89%).Conclusions The CAPD-related peritonitis in this center is mainly induced by Grampositive cocci Contact contamination is the main cause of peritonitis.The resistant rate of Gram-positive cocci to penicillin is highest,and that of Gram-negative bacilli to ampicillin/sulbactam is highest
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publisher Editorial Department of Journal of Clinical Nephrology
record_format Article
series Linchuang shenzangbing zazhi
spelling doaj-art-08f0e8ca08a74db09f862a2db6d94f872025-08-20T03:52:51ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902015-01-0118018457920949Pathogens and drug sensitivity analysis in 327 cases of peritoneal dialysis-related peritonitisWANG YipingWANG DongWANG Li-yuanJIN HuaLIU LingMAO Yan-pingLIU Jia-shengObjective To discuss the pathogens and drug resistance in continuous ambulatory peritoneal dialysis(CAPD)-related peritonitis.Methods The pathogens and drug resistance were retrospectively analyzed on 180 cases(327 cases/times) of CAPD-related peritonitis in our center from Jan2008 to May 2013.Results Positive cultures were seen in 202 cases/times with culture positive rate being 61.77%.There were 154 cases/times of gram-positive cocci,including 123 cases/times(60.89%) of Staphylococcus aureus and coagulase-negative staphylococci.There were 38 cases/times of gram-negative bacilli,including 11 cases/times(5.45%) of E.coll There were 10 cases/times of fungi,including 7 cases/times(3.47%) of Candida.The drug-resistant rate of gram-positive bacteria to vancomycin was lowest(3.25%),followed by moxifloxacin(5.19%),rifampin(12.99%),gentamicin(35.71%) and levofloxacin(45.45%),and that to penicillin highest(84.42%).The drug-resistant rate of gram-negative bacteria to piperacillin/tazobactam was lowest(10.53%),followed by ceftazidime(23.68%),levofloxacin(26.32%),cefpiramide US(36.84%),and that to ampicillin/sulbactam was highest(50.00%).Of 54 cases of repeated infections(114 cases/times).72 cases/times were positive with the culture positive rate being 63.16%,including 63 cases/times of Gram-positive cocci,predominantly Staphylococcus aureus,accounting for 87.50%,and 9 cases/times of Gram-negative bacilli,predominantly Escherichia coli,accounting for 12.50%.The drug-resistant rate of Grampositive cocci to vancomycin was lowestCl.59%),followed by moxifloxacin(3.17%),levofloxacin(15.87%) and gentamicin(55.56%),and that to penicillin was highest(95.24%).The drug-resistant rate of Gram-negative bacilli to piperacillin/tazobactam was lowest(11.11%),followed by ceftazidime(22.22%),levofloxacin(33.33%),gentamicin(55.56%),and that to ampicillin/sulbactam was highest(88.89%).Conclusions The CAPD-related peritonitis in this center is mainly induced by Grampositive cocci Contact contamination is the main cause of peritonitis.The resistant rate of Gram-positive cocci to penicillin is highest,and that of Gram-negative bacilli to ampicillin/sulbactam is highesthttp://www.lcszb.com/thesisDetails?columnId=57920949&Fpath=home&index=0Peritoneal dialysisPeritonitisTolerance
spellingShingle WANG Yiping
WANG Dong
WANG Li-yuan
JIN Hua
LIU Ling
MAO Yan-ping
LIU Jia-sheng
Pathogens and drug sensitivity analysis in 327 cases of peritoneal dialysis-related peritonitis
Linchuang shenzangbing zazhi
Peritoneal dialysis
Peritonitis
Tolerance
title Pathogens and drug sensitivity analysis in 327 cases of peritoneal dialysis-related peritonitis
title_full Pathogens and drug sensitivity analysis in 327 cases of peritoneal dialysis-related peritonitis
title_fullStr Pathogens and drug sensitivity analysis in 327 cases of peritoneal dialysis-related peritonitis
title_full_unstemmed Pathogens and drug sensitivity analysis in 327 cases of peritoneal dialysis-related peritonitis
title_short Pathogens and drug sensitivity analysis in 327 cases of peritoneal dialysis-related peritonitis
title_sort pathogens and drug sensitivity analysis in 327 cases of peritoneal dialysis related peritonitis
topic Peritoneal dialysis
Peritonitis
Tolerance
url http://www.lcszb.com/thesisDetails?columnId=57920949&Fpath=home&index=0
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AT wangdong pathogensanddrugsensitivityanalysisin327casesofperitonealdialysisrelatedperitonitis
AT wangliyuan pathogensanddrugsensitivityanalysisin327casesofperitonealdialysisrelatedperitonitis
AT jinhua pathogensanddrugsensitivityanalysisin327casesofperitonealdialysisrelatedperitonitis
AT liuling pathogensanddrugsensitivityanalysisin327casesofperitonealdialysisrelatedperitonitis
AT maoyanping pathogensanddrugsensitivityanalysisin327casesofperitonealdialysisrelatedperitonitis
AT liujiasheng pathogensanddrugsensitivityanalysisin327casesofperitonealdialysisrelatedperitonitis