Comparison of quality of life in patients after kidney transplantation under different regimens of immunosuppressive therapy
Background. Patients with chronic kidney disease, including dialysis patients, experience significant physical and mental stress, which ultimately leads to impaired physical and psychosocial health. All this significantly affects the quality of life. Kidney transplantation is the most promising dire...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Open Systems Publication
2025-01-01
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| Series: | Лечащий Врач |
| Subjects: | |
| Online Access: | https://journal.lvrach.ru/jour/article/view/1345 |
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| Summary: | Background. Patients with chronic kidney disease, including dialysis patients, experience significant physical and mental stress, which ultimately leads to impaired physical and psychosocial health. All this significantly affects the quality of life. Kidney transplantation is the most promising direction in providing medical care to patients with end-stage renal disease, since it provides a significant improvement in the quality of life compared to dialysis therapy. Understanding the specifics of the quality of life of patients who have undergone successful kidney transplantation can provide valuable information for making further therapeutic decisions.Objective. Analysis of the quality of life of kidney recipients under various regimens of immunosuppressive therapy.Materials and methods. A survey of 176 kidney recipients was conducted using the SF-36 questionnaire. The respondents were divided into 2 groups. The first group included recipients receiving immunosuppressive therapy at standard doses, the second group included recipients receiving immunosuppressive therapy at reduced doses.Results. The study showed a significant improvement in the quality of life in kidney transplant recipients 12 months after transplantation. Reducing the dosage of immunosuppressive drugs leads to a significant improvement in the quality of life of patients. This is due to a decrease in the frequency and severity of dose-dependent side effects of immunosuppressive therapy.Conclusion. Kidney and liver transplantation makes it possible to maintain sufficiently high rates of both the physical and psychological components of the quality of life. |
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| ISSN: | 1560-5175 2687-1181 |