The Value of MRI and Radiomics for the Diagnostic Evaluation of Thyroid-Associated Ophthalmopathy
Thyroid-associated ophthalmopathy (TAO) is a vision-threatening autoimmune disease that involves the extraocular muscles (EOMs) and periorbital fat. Typical signs of TAO include eyelid recession, proptosis, diplopia, and decreased visual acuity. As a self-limited disease, there is major bipolarity i...
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2025-02-01
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| author | Weiyi Zhou Yan Song Jufeng Shi Tuo Li |
| author_facet | Weiyi Zhou Yan Song Jufeng Shi Tuo Li |
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| description | Thyroid-associated ophthalmopathy (TAO) is a vision-threatening autoimmune disease that involves the extraocular muscles (EOMs) and periorbital fat. Typical signs of TAO include eyelid recession, proptosis, diplopia, and decreased visual acuity. As a self-limited disease, there is major bipolarity in clinical outcomes in TAO population. The early diagnosis and prediction of these refractory and relapsed patients is essential. Unfortunately, commonly used tools such as CAS/NOSPECTS, are based on clinical symptoms and signs alone, have significant limitations. Some imaging techniques or examinations, such as magnetic resonance imaging (MRI), can be very effective in assisting TAO assessment, from exhaustive whiteboard notes to optimized patient outcomes. Being one of the most commonly used and accurate objective examinations for TAO assessment, MRI boosts no ionizing radiation, high soft tissue contrast, better reflection of tissue water content, and the ability to quantify multiple parameters. In addition, novel MR sequences are becoming increasingly more familiar in TAO and other areas of clinical and scientific research. Moreover, radiomics, a method involving the extraction of a large number of features from medical images through algorithms, is a more recent approach used in the analysis and characterization of TAO data. Thus, this review aims to summarize and compare the value of routine and novel functional MRI sequences and radiomics prediction models in the diagnosis and evaluation of TAO. |
| format | Article |
| id | doaj-art-08e4285bca954744baaacd53f220e2cc |
| institution | OA Journals |
| issn | 2075-4418 |
| language | English |
| publishDate | 2025-02-01 |
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| spelling | doaj-art-08e4285bca954744baaacd53f220e2cc2025-08-20T02:12:41ZengMDPI AGDiagnostics2075-44182025-02-0115338810.3390/diagnostics15030388The Value of MRI and Radiomics for the Diagnostic Evaluation of Thyroid-Associated OphthalmopathyWeiyi Zhou0Yan Song1Jufeng Shi2Tuo Li3Department of Endocrinology, The Second Affiliated Hospital of Naval Medical University, Shanghai 200003, ChinaDepartment of Endocrinology, The Second Affiliated Hospital of Naval Medical University, Shanghai 200003, ChinaDepartment of Endocrinology, The Second Affiliated Hospital of Naval Medical University, Shanghai 200003, ChinaDepartment of Endocrinology, The Second Affiliated Hospital of Naval Medical University, Shanghai 200003, ChinaThyroid-associated ophthalmopathy (TAO) is a vision-threatening autoimmune disease that involves the extraocular muscles (EOMs) and periorbital fat. Typical signs of TAO include eyelid recession, proptosis, diplopia, and decreased visual acuity. As a self-limited disease, there is major bipolarity in clinical outcomes in TAO population. The early diagnosis and prediction of these refractory and relapsed patients is essential. Unfortunately, commonly used tools such as CAS/NOSPECTS, are based on clinical symptoms and signs alone, have significant limitations. Some imaging techniques or examinations, such as magnetic resonance imaging (MRI), can be very effective in assisting TAO assessment, from exhaustive whiteboard notes to optimized patient outcomes. Being one of the most commonly used and accurate objective examinations for TAO assessment, MRI boosts no ionizing radiation, high soft tissue contrast, better reflection of tissue water content, and the ability to quantify multiple parameters. In addition, novel MR sequences are becoming increasingly more familiar in TAO and other areas of clinical and scientific research. Moreover, radiomics, a method involving the extraction of a large number of features from medical images through algorithms, is a more recent approach used in the analysis and characterization of TAO data. Thus, this review aims to summarize and compare the value of routine and novel functional MRI sequences and radiomics prediction models in the diagnosis and evaluation of TAO.https://www.mdpi.com/2075-4418/15/3/388thyroid-associated ophthalmopathyTAOmagnetic resonance imagingMRIradiomicsdiagnosis |
| spellingShingle | Weiyi Zhou Yan Song Jufeng Shi Tuo Li The Value of MRI and Radiomics for the Diagnostic Evaluation of Thyroid-Associated Ophthalmopathy Diagnostics thyroid-associated ophthalmopathy TAO magnetic resonance imaging MRI radiomics diagnosis |
| title | The Value of MRI and Radiomics for the Diagnostic Evaluation of Thyroid-Associated Ophthalmopathy |
| title_full | The Value of MRI and Radiomics for the Diagnostic Evaluation of Thyroid-Associated Ophthalmopathy |
| title_fullStr | The Value of MRI and Radiomics for the Diagnostic Evaluation of Thyroid-Associated Ophthalmopathy |
| title_full_unstemmed | The Value of MRI and Radiomics for the Diagnostic Evaluation of Thyroid-Associated Ophthalmopathy |
| title_short | The Value of MRI and Radiomics for the Diagnostic Evaluation of Thyroid-Associated Ophthalmopathy |
| title_sort | value of mri and radiomics for the diagnostic evaluation of thyroid associated ophthalmopathy |
| topic | thyroid-associated ophthalmopathy TAO magnetic resonance imaging MRI radiomics diagnosis |
| url | https://www.mdpi.com/2075-4418/15/3/388 |
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