Long-term senolytic therapy with Dasatinib and Quercetin alleviates lipofuscin-dependent retinal degeneration in mice

Dry age-related macular degeneration (AMD) is one of the common blinding eye diseases, with pathological hallmarks of lipofuscin accumulation, neuroretina atrophy and retinal pigment epithelium (RPE) degeneration. Currently, there are no effective interventions for dry AMD. Although there is already...

Full description

Saved in:
Bibliographic Details
Main Authors: Bo Yang, Kunhuan Yang, Ruitong Xi, Shiying Li, Jingmeng Chen, Yalin Wu
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725002290
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items