Advances in Fluorescence Techniques for the Detection of Hydroxyl Radicals near DNA and Within Organelles and Membranes

Advances in Fluorescence Techniques for the Detection of Hydroxyl Radicals near DNA and Within Organelles and Membranes

Hydroxyl radicals (<sup>•</sup>OH), the most potent oxidants among reactive oxygen species (ROS), are a major contributor to oxidative damage of biomacromolecules, including DNA, lipids, and proteins. The overproduction of <sup>•</sup>OH is implicated in the pathogenesis of n...

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Bibliographic Details
Main Authors: Eleanor C. Ransdell-Green, Janina Baranowska-Kortylewicz, Dong Wang
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antioxidants
Subjects:
hydroxyl radicals
reactive oxygen species
fluorescence detection
DNA-targeting
organelle-targeting
coumarin-based probes
Online Access:https://www.mdpi.com/2076-3921/14/1/79
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