Treatment-resistant or difficult-to-treat depression: a consensus on the pharmacotherapy challenges and considerations for the health care system in Greece

Treatment-resistant or difficult-to-treat depression: a consensus on the pharmacotherapy challenges and considerations for the health care system in Greece

IntroductionGlobally, there is limited scientific consensus on the definition of Treatment Resistant Depression (TRD) or Difficult to Treat Depression (DTD) and even greater challenges are being reported with its management. In Greece, the last available guidelines on depression from 2015 make no re...

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Bibliographic Details
Main Authors: Kyriakos Souliotis, Christina Golna, Myrto Samara, Eva-Maria Tsapakis, Vasilios P. Bozikas, Thomas N. Hyphantis, Nikolaos Smyrnis, Nikos Stefanis
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Psychiatry
Subjects:
treatment resistant depression (TRD)
difficult to treat depression (DTD)
depression
integrated healthcare delivery
mental health policy
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1561821/full
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