Acute Systemic Viral Infection Masquerading as an Infiltrating Lymphoma in an Elderly Patient: A Case Report and Review of the Literature

Primary Epstein-Barr virus (EBV) infection occurs mainly in adolescents and young adults, with more than 90% of adults having serological evidence of past infection. Primary infection in those over the age of 40 is associated with an atypical and often more severe presentation that can lead to more...

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Main Authors: Hani M. Babiker, Troy Wiedenbeck, Ryan S. Robetorye, Utkarsh Acharya, Susan Wilansky, Shimon Kusne
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/318358
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author Hani M. Babiker
Troy Wiedenbeck
Ryan S. Robetorye
Utkarsh Acharya
Susan Wilansky
Shimon Kusne
author_facet Hani M. Babiker
Troy Wiedenbeck
Ryan S. Robetorye
Utkarsh Acharya
Susan Wilansky
Shimon Kusne
author_sort Hani M. Babiker
collection DOAJ
description Primary Epstein-Barr virus (EBV) infection occurs mainly in adolescents and young adults, with more than 90% of adults having serological evidence of past infection. Primary infection in those over the age of 40 is associated with an atypical and often more severe presentation that can lead to more extensive and invasive, and often unnecessary, diagnostic testing. The incidence of severe EBV-related illness in older adults has been observed to be increasing in industrialized nations. The characteristic presentation of infectious mononucleosis (IM) syndrome in elderly patients (age > 65) is not clearly defined in the literature. Here, we describe a case of primary EBV infection in an 80-year-old female and review the literature regarding primary seroconversion in elderly patients.
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spelling doaj-art-08d71f1254b246a6ba4f8736ef23e7c82025-08-20T02:03:20ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/318358318358Acute Systemic Viral Infection Masquerading as an Infiltrating Lymphoma in an Elderly Patient: A Case Report and Review of the LiteratureHani M. Babiker0Troy Wiedenbeck1Ryan S. Robetorye2Utkarsh Acharya3Susan Wilansky4Shimon Kusne5Division of Hematology and Oncology, The University of Arizona Cancer Center, 1515 N Campbell Avenue, Tucson, AZ 85724, USADivision of Cardiology, Mayo Clinic, 5777 E Mayo Boulevard, Phoenix, AZ 85054, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, 5777 E Mayo Boulevard, Phoenix, AZ 85054, USADivision of Hematology and Oncology, The University of Arizona Cancer Center, 1515 N Campbell Avenue, Tucson, AZ 85724, USADivision of Cardiology, Mayo Clinic, 5777 E Mayo Boulevard, Phoenix, AZ 85054, USADivision of Infectious Diseases, Mayo Clinic, 5777 E Mayo Boulevard, Phoenix, AZ 85054, USAPrimary Epstein-Barr virus (EBV) infection occurs mainly in adolescents and young adults, with more than 90% of adults having serological evidence of past infection. Primary infection in those over the age of 40 is associated with an atypical and often more severe presentation that can lead to more extensive and invasive, and often unnecessary, diagnostic testing. The incidence of severe EBV-related illness in older adults has been observed to be increasing in industrialized nations. The characteristic presentation of infectious mononucleosis (IM) syndrome in elderly patients (age > 65) is not clearly defined in the literature. Here, we describe a case of primary EBV infection in an 80-year-old female and review the literature regarding primary seroconversion in elderly patients.http://dx.doi.org/10.1155/2013/318358
spellingShingle Hani M. Babiker
Troy Wiedenbeck
Ryan S. Robetorye
Utkarsh Acharya
Susan Wilansky
Shimon Kusne
Acute Systemic Viral Infection Masquerading as an Infiltrating Lymphoma in an Elderly Patient: A Case Report and Review of the Literature
Case Reports in Medicine
title Acute Systemic Viral Infection Masquerading as an Infiltrating Lymphoma in an Elderly Patient: A Case Report and Review of the Literature
title_full Acute Systemic Viral Infection Masquerading as an Infiltrating Lymphoma in an Elderly Patient: A Case Report and Review of the Literature
title_fullStr Acute Systemic Viral Infection Masquerading as an Infiltrating Lymphoma in an Elderly Patient: A Case Report and Review of the Literature
title_full_unstemmed Acute Systemic Viral Infection Masquerading as an Infiltrating Lymphoma in an Elderly Patient: A Case Report and Review of the Literature
title_short Acute Systemic Viral Infection Masquerading as an Infiltrating Lymphoma in an Elderly Patient: A Case Report and Review of the Literature
title_sort acute systemic viral infection masquerading as an infiltrating lymphoma in an elderly patient a case report and review of the literature
url http://dx.doi.org/10.1155/2013/318358
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