Challenges in diagnosing and managing sarcomatoid urothelial carcinoma of the renal pelvis: a case report
Sarcomatoid urothelial carcinoma of the renal pelvis is an extremely rare malignant tumor with a high risk of recurrence and metastasis and a poor prognosis. This case reports a 61-year-old male patient with renal pelvic sarcomatoid urothelial carcinoma who developed extensive lymph node metastasis...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1480790/full |
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| author | Jian Lei Wei Zhao Tao He Hui Huang Huayong Jian Mei Zhang Xike Luo Xiaochuan Gong Yan Wang |
| author_facet | Jian Lei Wei Zhao Tao He Hui Huang Huayong Jian Mei Zhang Xike Luo Xiaochuan Gong Yan Wang |
| author_sort | Jian Lei |
| collection | DOAJ |
| description | Sarcomatoid urothelial carcinoma of the renal pelvis is an extremely rare malignant tumor with a high risk of recurrence and metastasis and a poor prognosis. This case reports a 61-year-old male patient with renal pelvic sarcomatoid urothelial carcinoma who developed extensive lymph node metastasis 26 days after posterior laparoscopic radical nephrectomy for renal carcinoma, and the patient died on the 45th postoperative day, with the cause of death being advanced malignancy of the tumor. This case highlights the rapid progression of sarcomatoid urothelial carcinoma, and sarcomatoid variants should be identified as early as possible, with active multidisciplinary adjuvant therapy and closer follow-up when feasible. Retrospective analysis of this patient’s treatment regimen and admission provides lessons for recognizing and aggressively managing this rare and fatal variant of urothelial carcinoma. |
| format | Article |
| id | doaj-art-08d66a3e875f46bdbbc3efa2efbf23e6 |
| institution | DOAJ |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-08d66a3e875f46bdbbc3efa2efbf23e62025-08-20T03:11:25ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-02-011510.3389/fonc.2025.14807901480790Challenges in diagnosing and managing sarcomatoid urothelial carcinoma of the renal pelvis: a case reportJian Lei0Wei Zhao1Tao He2Hui Huang3Huayong Jian4Mei Zhang5Xike Luo6Xiaochuan Gong7Yan Wang8Department of Urology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaDepartment of Urology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaDepartment of Urology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaDepartment of Urology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaDepartment of Pathology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaDepartment of Obstetrics, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaDepartment of Urology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaDepartment of Urology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaDepartment of Urology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaSarcomatoid urothelial carcinoma of the renal pelvis is an extremely rare malignant tumor with a high risk of recurrence and metastasis and a poor prognosis. This case reports a 61-year-old male patient with renal pelvic sarcomatoid urothelial carcinoma who developed extensive lymph node metastasis 26 days after posterior laparoscopic radical nephrectomy for renal carcinoma, and the patient died on the 45th postoperative day, with the cause of death being advanced malignancy of the tumor. This case highlights the rapid progression of sarcomatoid urothelial carcinoma, and sarcomatoid variants should be identified as early as possible, with active multidisciplinary adjuvant therapy and closer follow-up when feasible. Retrospective analysis of this patient’s treatment regimen and admission provides lessons for recognizing and aggressively managing this rare and fatal variant of urothelial carcinoma.https://www.frontiersin.org/articles/10.3389/fonc.2025.1480790/fullrenal pelvis sarcomatoid urothelial carcinomarare diseaseposterior laparoscopic radical nephrectomy for renal cancerpathologydiagnosisprognosis |
| spellingShingle | Jian Lei Wei Zhao Tao He Hui Huang Huayong Jian Mei Zhang Xike Luo Xiaochuan Gong Yan Wang Challenges in diagnosing and managing sarcomatoid urothelial carcinoma of the renal pelvis: a case report Frontiers in Oncology renal pelvis sarcomatoid urothelial carcinoma rare disease posterior laparoscopic radical nephrectomy for renal cancer pathology diagnosis prognosis |
| title | Challenges in diagnosing and managing sarcomatoid urothelial carcinoma of the renal pelvis: a case report |
| title_full | Challenges in diagnosing and managing sarcomatoid urothelial carcinoma of the renal pelvis: a case report |
| title_fullStr | Challenges in diagnosing and managing sarcomatoid urothelial carcinoma of the renal pelvis: a case report |
| title_full_unstemmed | Challenges in diagnosing and managing sarcomatoid urothelial carcinoma of the renal pelvis: a case report |
| title_short | Challenges in diagnosing and managing sarcomatoid urothelial carcinoma of the renal pelvis: a case report |
| title_sort | challenges in diagnosing and managing sarcomatoid urothelial carcinoma of the renal pelvis a case report |
| topic | renal pelvis sarcomatoid urothelial carcinoma rare disease posterior laparoscopic radical nephrectomy for renal cancer pathology diagnosis prognosis |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1480790/full |
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